Gene Symbol: rnc
Description: ribonuclease III
Species: Escherichia coli O157:H7 str. Sakai

Top Publications

  1. March P, Ahnn J, Inouye M. The DNA sequence of the gene (rnc) encoding ribonuclease III of Escherichia coli. Nucleic Acids Res. 1985;13:4677-85 pubmed
    The DNA sequence of a 1,076 base pair BglI-BamHI fragment containing the entire rnc gene for ribonuclease III (RNase III) was determined...
  2. Hiratsu K, Amemura M, Nashimoto H, Shinagawa H, Makino K. The rpoE gene of Escherichia coli, which encodes sigma E, is essential for bacterial growth at high temperature. J Bacteriol. 1995;177:2918-22 pubmed
    ..We demonstrate that expression of htrA is completely dependent on the rpoE gene in vivo and that the rpoE gene is essential for bacterial growth at high temperature. ..
  3. Paudyal S, Alfonso Prieto M, Carnevale V, Redhu S, Klein M, Nicholson A. Combined computational and experimental analysis of a complex of ribonuclease III and the regulatory macrodomain protein, YmdB. Proteins. 2015;83:459-72 pubmed publisher
    ..The features of the modeled complex relevant to potential RNase III regulatory mechanisms are discussed. ..
  4. Poulsen L, Larsen N, Molin S, Andersson P. Analysis of an Escherichia coli mutant strain resistant to the cell-killing function encoded by the gef gene family. Mol Microbiol. 1992;6:895-905 pubmed
    ..1 kDa. ORF178 and an upstream frame, ORF190, probably constitute an operon...
  5. Varshney U, Hutcheon T, van de Sande J. Sequence analysis, expression, and conservation of Escherichia coli uracil DNA glycosylase and its gene (ung). J Biol Chem. 1988;263:7776-84 pubmed
    ..No sequence homologies were seen for Pseudomonas, Clostridium, Micrococcus, and several eukaryotic genomes. ..
  6. Flachmann R, Kunz N, Seifert J, G tlich M, Wientjes F, L ufer A, et al. Molecular biology of pyridine nucleotide biosynthesis in Escherichia coli. Cloning and characterization of quinolinate synthesis genes nadA and nadB. Eur J Biochem. 1988;175:221-8 pubmed
    ..High-copy-number vectors, carrying either gene nadA, nadB or nadA + nadB, increased quinolinate production 1.5-fold, 2.0-fold and 15-fold respectively. Both gene products seem to be equally rate-limiting in quinolinate synthesis...
  7. March P, Inouye M. Characterization of the lep operon of Escherichia coli. Identification of the promoter and the gene upstream of the signal peptidase I gene. J Biol Chem. 1985;260:7206-13 pubmed
    ..The DNA sequence immediately downstream of the lep gene contains features consistent with a rho factor-independent transcriptional termination site, indicating that the lep operon encodes only two proteins (lepA and lep). ..
  8. Morrison P, Lovett S, Gilson L, Kolodner R. Molecular analysis of the Escherichia coli recO gene. J Bacteriol. 1989;171:3641-9 pubmed
    The plasmid pLC7-47, which contains lep, rnc, and era, was found to complement the UV-sensitive and recombination-deficient phenotypes caused by the recO1504::Tn5 mutation...
  9. Ahnn J, March P, Takiff H, Inouye M. A GTP-binding protein of Escherichia coli has homology to yeast RAS proteins. Proc Natl Acad Sci U S A. 1986;83:8849-53 pubmed
    The DNA sequence of a gene (era) located immediately downstream of the gene (rnc) encoding ribonuclease III of Escherichia coli was determined and found to encode a protein of 316 amino acid residues...

More Information


  1. Yu H, Schurr M, Deretic V. Functional equivalence of Escherichia coli sigma E and Pseudomonas aeruginosa AlgU: E. coli rpoE restores mucoidy and reduces sensitivity to reactive oxygen intermediates in algU mutants of P. aeruginosa. J Bacteriol. 1995;177:3259-68 pubmed
    ..aeruginosa and suggest that elements showing sequence similarity to those known to regulate AlgU activity in P. aeruginosa are also present in other bacteria...
  2. Takiff H, Chen S, Court D. Genetic analysis of the rnc operon of Escherichia coli. J Bacteriol. 1989;171:2581-90 pubmed
    ..Clones of the region of the E. coli chromosome containing the gene for RNase III (rnc) were obtained by screening genomic libraries in lambda with DNA known to map near rnc...
  3. Nashimoto H, Uchida H. DNA sequencing of the Escherichia coli ribonuclease III gene and its mutations. Mol Gen Genet. 1985;201:25-9 pubmed
    A 0.7 kb DNA fragment of the Escherichia coli K12 chromosome was shown to contain the structural gene for RNAse III (rnc)...