Gene Symbol: ralR
Description: Rac prophage; restriction alleviation protein
Alias: ECK1345, JW5208, lar, ral, ydaB
Species: Escherichia coli str. K-12 substr. MG1655

Top Publications

  1. King G, Murray N. Restriction alleviation and modification enhancement by the Rac prophage of Escherichia coli K-12. Mol Microbiol. 1995;16:769-77 pubmed
    ..Here we report the characterization of an analogous function, Lar, expressed by E. coli sbcA mutants and the hybrid phage lambda reverse. E...
  2. Blakely G, Murray N. Control of the endonuclease activity of type I restriction-modification systems is required to maintain chromosome integrity following homologous recombination. Mol Microbiol. 2006;60:883-93 pubmed
    ..the primary pathway in which ClpXP degrades the restriction endonuclease and a mechanism dependent on the lar gene within Rac, a resident, defective prophage of E. coli K-12...
  3. Toothman P. Restriction alleviation by bacteriophages lambda and lambda reverse. J Virol. 1981;38:621-31 pubmed
    Deletion analysis indicated that the phage lambda restriction alleviation gene(s) ral resides between the cIII and N genes...
  4. Clark A, Sharma V, Brenowitz S, Chu C, Sandler S, Satin L, et al. Genetic and molecular analyses of the C-terminal region of the recE gene from the Rac prophage of Escherichia coli K-12 reveal the recT gene. J Bacteriol. 1993;175:7673-82 pubmed
    ..5-kb portion of the b2 region of lambda. This suggests interesting speculations concerning the evolutionary relationship of lambda and Rac prophages. ..
  5. Handa N, Kobayashi I. Type III restriction is alleviated by bacteriophage (RecE) homologous recombination function but enhanced by bacterial (RecBCD) function. J Bacteriol. 2005;187:7362-73 pubmed
    ..This type III restriction alleviation does not depend on lar on Rac, unlike type I restriction alleviation...
  6. Guo Y, Quiroga C, Chen Q, McAnulty M, Benedik M, Wood T, et al. RalR (a DNase) and RalA (a small RNA) form a type I toxin-antitoxin system in Escherichia coli. Nucleic Acids Res. 2014;42:6448-62 pubmed publisher
    ..Here, we demonstrate that RalR and RalA of the cryptic prophage rac form a type I TA pair in which the antitoxin RNA is a trans-encoded small RNA ..
  7. Simmon V, Lederberg S. Degradation of bacteriophage lambda deoxyribonucleic acid after restriction by Escherichia coli K-12. J Bacteriol. 1972;112:161-9 pubmed
    ..The presence of a functional lambda exonuclease gene is not required for degradation after restriction. ..