prfA

Summary

Gene Symbol: prfA
Description: peptide chain release factor 1
Species: Escherichia coli CFT073

Top Publications

  1. pmc Isolation, nucleotide sequence, and preliminary characterization of the Escherichia coli K-12 hemA gene
    E Verkamp
    Department of Energy Plant Research Laboratory, Michigan State University, East Lansing 48824 1312
    J Bacteriol 171:4728-35. 1989
  2. ncbi Cloning and structure of the hem A gene of Escherichia coli K-12
    J M Li
    Department of Biochemistry Biology City College, City University of New York, NY 10031
    Gene 82:209-17. 1989
  3. pmc Rapid and precise mapping of the Escherichia coli release factor genes by two physical approaches
    C C Lee
    Institute for Molecular Genetics, Baylor College of Medicine, Houston, Texas 77030
    J Bacteriol 170:4537-41. 1988
  4. pmc Bacterial peptide chain release factors: conserved primary structure and possible frameshift regulation of release factor 2
    W J Craigen
    Proc Natl Acad Sci U S A 82:3616-20. 1985
  5. pmc Expression of genes kdsA and kdsB involved in 3-deoxy-D-manno-octulosonic acid metabolism and biosynthesis of enterobacterial lipopolysaccharide is growth phase regulated primarily at the transcriptional level in Escherichia coli K-12
    H Strohmaier
    Institute of Microbiology, University of Graz, Austria
    J Bacteriol 177:4488-500. 1995
  6. ncbi Cloning and sequencing of a previously unidentified gene that is involved in the biosynthesis of heme in Escherichia coli
    T Nakayashiki
    Department of Biophysics, Faculty of Science, Kyoto University, Japan
    Gene 153:67-70. 1995
  7. pmc A post-translational modification in the GGQ motif of RF2 from Escherichia coli stimulates termination of translation
    V Dincbas-Renqvist
    Department of Cell and Molecular Biology and Department of Medical Biochemistry and Microbiology, Uppsala University, BMC, S 751 24, Uppsala, Sweden
    EMBO J 19:6900-7. 2000
  8. ncbi Effects of two cis-acting mutations on the regulation and expression of release factor one in Escherichia coli
    Ann Dahlgren
    Department of Genetics, Microbiology, and Toxicology, Stockholm University, 106 91 Stockholm, Sweden
    Biochimie 86:431-8. 2004

Detail Information

Publications8

  1. pmc Isolation, nucleotide sequence, and preliminary characterization of the Escherichia coli K-12 hemA gene
    E Verkamp
    Department of Energy Plant Research Laboratory, Michigan State University, East Lansing 48824 1312
    J Bacteriol 171:4728-35. 1989
    ..Furthermore, DNA sequence analysis established that the cloned gene lay directly upstream of prfA, which encodes polypeptide chain release factor 1...
  2. ncbi Cloning and structure of the hem A gene of Escherichia coli K-12
    J M Li
    Department of Biochemistry Biology City College, City University of New York, NY 10031
    Gene 82:209-17. 1989
    ..7 and mapping it precisely near RF1. We have shown that E. coli utilizes the intact five-carbon chain of glutamate for the synthesis of ALA [Li et al., J Bacteriol. 171 (1989b) 2547-2552]...
  3. pmc Rapid and precise mapping of the Escherichia coli release factor genes by two physical approaches
    C C Lee
    Institute for Molecular Genetics, Baylor College of Medicine, Houston, Texas 77030
    J Bacteriol 170:4537-41. 1988
    ..The RF2 gene is located at 62.3 min on the chromosome, while the RF1 gene is located at 26.7 min. This approach to mapping cloned genes promises to be a rapid and simple means for determining the gene order of the genome...
  4. pmc Bacterial peptide chain release factors: conserved primary structure and possible frameshift regulation of release factor 2
    W J Craigen
    Proc Natl Acad Sci U S A 82:3616-20. 1985
    ..This may represent a mechanism of translational control of RF-2 expression. An alternative possible means of translational regulation is discussed...
  5. pmc Expression of genes kdsA and kdsB involved in 3-deoxy-D-manno-octulosonic acid metabolism and biosynthesis of enterobacterial lipopolysaccharide is growth phase regulated primarily at the transcriptional level in Escherichia coli K-12
    H Strohmaier
    Institute of Microbiology, University of Graz, Austria
    J Bacteriol 177:4488-500. 1995
    ..We have also identified two other genes, hemA and prfA, at the beginning of the cluster...
  6. ncbi Cloning and sequencing of a previously unidentified gene that is involved in the biosynthesis of heme in Escherichia coli
    T Nakayashiki
    Department of Biophysics, Faculty of Science, Kyoto University, Japan
    Gene 153:67-70. 1995
    ..coli chromosome. By nucleotide (nt) sequencing, it was demonstrated that hemK forms part of the hemA-prfA-hemK operon and encodes 225 amino acids that show no significant homology to any protein in the standard databases...
  7. pmc A post-translational modification in the GGQ motif of RF2 from Escherichia coli stimulates termination of translation
    V Dincbas-Renqvist
    Department of Cell and Molecular Biology and Department of Medical Biochemistry and Microbiology, Uppsala University, BMC, S 751 24, Uppsala, Sweden
    EMBO J 19:6900-7. 2000
    ..We propose that the previously observed lethal effect of overproducing E.coli K12 RF2 arises through accumulating the defects due to lack of Gln252 methylation and Thr246 in place of alanine...
  8. ncbi Effects of two cis-acting mutations on the regulation and expression of release factor one in Escherichia coli
    Ann Dahlgren
    Department of Genetics, Microbiology, and Toxicology, Stockholm University, 106 91 Stockholm, Sweden
    Biochimie 86:431-8. 2004
    ..b>prfA, the gene that codes for RF1, is located at 27 min on the Escherichia coli map as the second gene in the hemA-..