Gene Symbol: pgpC
Description: phosphatidylglycerophosphatase C, membrane bound
Alias: ECK2558, JW5408, yfhB
Species: Escherichia coli str. K-12 substr. MG1655

Top Publications

  1. Funk C, Zimniak L, Dowhan W. The pgpA and pgpB genes of Escherichia coli are not essential: evidence for a third phosphatidylglycerophosphate phosphatase. J Bacteriol. 1992;174:205-13 pubmed
    ..coli phospholipid biosynthesis for which a gene locus has not been identified. ..
  2. Poulsen L, Larsen N, Molin S, Andersson P. Analysis of an Escherichia coli mutant strain resistant to the cell-killing function encoded by the gef gene family. Mol Microbiol. 1992;6:895-905 pubmed
    ..1 kDa. ORF178 and an upstream frame, ORF190, probably constitute an operon...
  3. Icho T, Raetz C. Multiple genes for membrane-bound phosphatases in Escherichia coli and their action on phospholipid precursors. J Bacteriol. 1983;153:722-30 pubmed
    ..coli, both distinct from alkaline phosphatase. The pgpA gene product is specific for PGP, whereas the pgpB gene product also acts on phosphatidic acid and lysophosphatidic acid. ..
  4. Dillon D, Wu W, Riedel B, Wissing J, Dowhan W, Carman G. The Escherichia coli pgpB gene encodes for a diacylglycerol pyrophosphate phosphatase activity. J Biol Chem. 1996;271:30548-53 pubmed
    ..Pure DGPP phosphatase from Saccharomyces cerevisiae was shown to be similar to the E. coli DGPP phosphatase in its ability to utilize lyso-PA and phosphatidylglycerophosphate as substrates in vitro. ..
  5. El Ghachi M, Derbise A, Bouhss A, Mengin Lecreulx D. Identification of multiple genes encoding membrane proteins with undecaprenyl pyrophosphate phosphatase (UppP) activity in Escherichia coli. J Biol Chem. 2005;280:18689-95 pubmed
    ..coli and probably other bacterial species; they are the BacA enzyme and several members from a superfamily of phosphatases that, different from BacA, share in common a characteristic phosphatase sequence motif. ..
  6. Lu Y, Guan Z, Zhao J, Raetz C. Three phosphatidylglycerol-phosphate phosphatases in the inner membrane of Escherichia coli. J Biol Chem. 2011;286:5506-18 pubmed publisher
    ..We have identified a third PGP-phosphatase gene (previously annotated as yfhB but renamed pgpC) using an expression cloning strategy...