Gene Symbol: panF
Description: pantothenate:sodium symporter
Alias: ECK3245, JW3226
Species: Escherichia coli str. K-12 substr. MG1655
Reizer J, Reizer A, Saier M. The Na+/pantothenate symporter (PanF) of Escherichia coli is homologous to the Na+/proline symporter (PutP) of E. coli and the Na+/glucose symporters of mammals. Res Microbiol. 1990;141:1069-72 pubmed
Vallari D, Rock C. Isolation and characterization of Escherichia coli pantothenate permease (panF) mutants. J Bacteriol. 1985;164:136-42 pubmed
Mutants of Escherichia coli K-12 defective in the pantothenate permease (panF) were isolated and characterized...
Vanet A, Plumbridge J, Alix J. Cotranscription of two genes necessary for ribosomal protein L11 methylation (prmA) and pantothenate transport (panF) in Escherichia coli K-12. J Bacteriol. 1993;175:7178-88 pubmed
Genetic complementation and enzyme assays have shown that the DNA region between panF, which encodes pantothenate permease, and orf1, the first gene of the fis operon, encodes prmA, the genetic determinant for the ribosomal protein L11 ..
Jackowski S, Alix J. Cloning, sequence, and expression of the pantothenate permease (panF) gene of Escherichia coli. J Bacteriol. 1990;172:3842-8 pubmed
Pantothenate permease, the product of the panF gene, catalyzes the sodium-dependent uptake of extracellular pantothenate. The panF gene was isolated from an Escherichia coli genomic DNA library and subcloned into multicopy plasmids...
Vallari D, Rock C. Pantothenate transport in Escherichia coli. J Bacteriol. 1985;162:1156-61 pubmed
..The data were consistent with the presence of a high-affinity pantothenate permease that concentrates the vitamin by sodium cotransport. ..
Reizer J, Reizer A, Saier M. A functional superfamily of sodium/solute symporters. Biochim Biophys Acta. 1994;1197:133-66 pubmed
..This study serves to clarify structural, functional and evolutionary relationships among eleven distinct families of functionally related transport proteins. ..