Gene Symbol: nrfA
Description: cytochrome c552
Species: Escherichia coli O157:H7 str. Sakai

Top Publications

  1. Darwin A, Hussain H, Griffiths L, Grove J, Sambongi Y, Busby S, et al. Regulation and sequence of the structural gene for cytochrome c552 from Escherichia coli: not a hexahaem but a 50 kDa tetrahaem nitrite reductase. Mol Microbiol. 1993;9:1255-65 pubmed
    The structural gene, nrfA, for cytochrome c552, which is the terminal reductase of the formate-dependent pathway for nitrite reduction to ammonia, has been located at co-ordinate 4366 on the physical map of the Escherichia coli chromosome...
  2. Iobbi Nivol C, Crooke H, Griffiths L, Grove J, Hussain H, Pommier J, et al. A reassessment of the range of c-type cytochromes synthesized by Escherichia coli K-12. FEMS Microbiol Lett. 1994;119:89-94 pubmed
    ..No other c-type cytochrome was detected under any growth condition tested. ..
  3. Pope N, Cole J. Pyruvate and ethanol as electron donors for nitrite reduction by Escherichia coli K12. J Gen Microbiol. 1984;130:1279-84 pubmed
    ..We conclude that any third pathway for nitrite reduction contributes little to the in vivo rate of nitrite reduction by wild-type strains. ..
  4. Hussain H, Grove J, Griffiths L, Busby S, Cole J. A seven-gene operon essential for formate-dependent nitrite reduction to ammonia by enteric bacteria. Mol Microbiol. 1994;12:153-63 pubmed
    The DNA sequence of the regulatory region and the structural gene, nrfA, for cytochrome c552 of Escherichia coli K-12 have been reported...
  5. Eaves D, Grove J, Staudenmann W, James P, Poole R, White S, et al. Involvement of products of the nrfEFG genes in the covalent attachment of haem c to a novel cysteine-lysine motif in the cytochrome c552 nitrite reductase from Escherichia coli. Mol Microbiol. 1998;28:205-16 pubmed four 'typical' haem-binding motifs, CXXCH-, characteristic of c-type cytochromes, the N-terminal region of NrfA includes a motif, CWSCK...
  6. Fujita T. Studies on soluble cytochromes in Enterobacteriaceae. I. Detection, purification, and properties of cytochrome c-552 in anaerobically grown cells. J Biochem. 1966;60:204-15 pubmed
  7. Darwin A, Tormay P, Page L, Griffiths L, Cole J. Identification of the formate dehydrogenases and genetic determinants of formate-dependent nitrite reduction by Escherichia coli K12. J Gen Microbiol. 1993;139:1829-40 pubmed
  8. Bamford V, Angove H, Seward H, Thomson A, Cole J, Butt J, et al. Structure and spectroscopy of the periplasmic cytochrome c nitrite reductase from Escherichia coli. Biochemistry. 2002;41:2921-31 pubmed
    The crystal structure and spectroscopic properties of the periplasmic penta-heme cytochrome c nitrite reductase (NrfA) of Escherichia coli are presented...
  9. Siniachenko O, Diadyk A, Vasilenko I, Kobets V. [Clinical course of nephropathy in gout starting in youth]. Revmatologiia (Mosk). 1985;:19-22 pubmed