Gene Symbol: nrfA
Description: cytochrome c552
Species: Escherichia coli O157:H7 str. Sakai
Darwin A, Hussain H, Griffiths L, Grove J, Sambongi Y, Busby S, et al
. Regulation and sequence of the structural gene for cytochrome c552 from Escherichia coli: not a hexahaem but a 50 kDa tetrahaem nitrite reductase. Mol Microbiol. 1993;9:1255-65 pubmed
The structural gene, nrfA, for cytochrome c552, which is the terminal reductase of the formate-dependent pathway for nitrite reduction to ammonia, has been located at co-ordinate 4366 on the physical map of the Escherichia coli chromosome...
Iobbi Nivol C, Crooke H, Griffiths L, Grove J, Hussain H, Pommier J, et al
. A reassessment of the range of c-type cytochromes synthesized by Escherichia coli K-12. FEMS Microbiol Lett. 1994;119:89-94 pubmed
..No other c-type cytochrome was detected under any growth condition tested. ..
Pope N, Cole J. Pyruvate and ethanol as electron donors for nitrite reduction by Escherichia coli K12. J Gen Microbiol. 1984;130:1279-84 pubmed
..We conclude that any third pathway for nitrite reduction contributes little to the in vivo rate of nitrite reduction by wild-type strains. ..
Hussain H, Grove J, Griffiths L, Busby S, Cole J. A seven-gene operon essential for formate-dependent nitrite reduction to ammonia by enteric bacteria. Mol Microbiol. 1994;12:153-63 pubmed
The DNA sequence of the regulatory region and the structural gene, nrfA, for cytochrome c552 of Escherichia coli K-12 have been reported...
Eaves D, Grove J, Staudenmann W, James P, Poole R, White S, et al
. Involvement of products of the nrfEFG genes in the covalent attachment of haem c to a novel cysteine-lysine motif in the cytochrome c552 nitrite reductase from Escherichia coli. Mol Microbiol. 1998;28:205-16 pubmed
..to four 'typical' haem-binding motifs, CXXCH-, characteristic of c-type cytochromes, the N-terminal region of NrfA includes a motif, CWSCK...
Fujita T. Studies on soluble cytochromes in Enterobacteriaceae. I. Detection, purification, and properties of cytochrome c-552 in anaerobically grown cells. J Biochem. 1966;60:204-15 pubmed
Darwin A, Tormay P, Page L, Griffiths L, Cole J. Identification of the formate dehydrogenases and genetic determinants of formate-dependent nitrite reduction by Escherichia coli K12. J Gen Microbiol. 1993;139:1829-40 pubmed
Bamford V, Angove H, Seward H, Thomson A, Cole J, Butt J, et al
. Structure and spectroscopy of the periplasmic cytochrome c nitrite reductase from Escherichia coli. Biochemistry. 2002;41:2921-31 pubmed
The crystal structure and spectroscopic properties of the periplasmic penta-heme cytochrome c nitrite reductase (NrfA) of Escherichia coli are presented...
Siniachenko O, Diadyk A, Vasilenko I, Kobets V. [Clinical course of nephropathy in gout starting in youth]. Revmatologiia (Mosk). 1985;:19-22 pubmed