Genomes and Genes
Gene Symbol: nrdE
Description: ribonucleoside-diphosphate reductase 2, alpha subunit
Alias: ECK2669, JW2650
Species: Escherichia coli str. K-12 substr. MG1655
- Kolberg M, Strand K, Graff P, Andersson K. Structure, function, and mechanism of ribonucleotide reductases. Biochim Biophys Acta. 2004;1699:1-34 pubmed
- Justino M, Vicente J, Teixeira M, Saraiva L. New genes implicated in the protection of anaerobically grown Escherichia coli against nitric oxide. J Biol Chem. 2005;280:2636-43 pubmed..coli gene transcription profile that includes the increase of the transcript level of genes encoding for detoxification enzymes, iron-sulfur cluster assembly systems, DNA-repairing enzymes, and stress response regulators. ..
- Torrents E, Grinberg I, Gorovitz Harris B, Lundström H, Borovok I, Aharonowitz Y, et al. NrdR controls differential expression of the Escherichia coli ribonucleotide reductase genes. J Bacteriol. 2007;189:5012-21 pubmed..The model assumes that differences in the positions of the NrdR binding sites, and in the sequences of the motifs themselves, determine the extent to which NrdR represses the transcription of each RNR operon. ..
- Minnihan E, Seyedsayamdost M, Stubbe J. Use of 3-aminotyrosine to examine the pathway dependence of radical propagation in Escherichia coli ribonucleotide reductase. Biochemistry. 2009;48:12125-32 pubmed publisher..2-0.3% of that observed at 731 and 730, and with (c), no NH(2)Y(*) was observed. These studies suggest the evolution of an optimized pathway of conserved Ys in the oxidation of C(439). ..