Gene Symbol: mokC
Description: regulatory protein for HokC, overlaps CDS of hokC
Alias: ECK4466, gefL
Species: Escherichia coli str. K-12 substr. MG1655

Top Publications

  1. Poulsen L, Refn A, Molin S, Andersson P. The gef gene from Escherichia coli is regulated at the level of translation. Mol Microbiol. 1991;5:1639-48 pubmed
    ..We demonstrate here that translation of gef is coupled to an upstream open reading frame which, in turn, is regulated by a transacting factor, probably an antisense RNA. ..
  2. Gerdes K, Gultyaev A, Franch T, Pedersen K, Mikkelsen N. Antisense RNA-regulated programmed cell death. Annu Rev Genet. 1997;31:1-31 pubmed
    ..The complex phylogenetic relationships of the plasmid- and chromosome-encoded systems are also presented and discussed. ..
  3. Pedersen K, Gerdes K. Multiple hok genes on the chromosome of Escherichia coli. Mol Microbiol. 1999;32:1090-102 pubmed
    ..The chromosome-encoded mRNAs are poorly translated in vitro, thus yielding an explanation for the lacking phenotype. These observations suggest that the chromosomal hok-like genes may be induced by an as yet unknown signal. ..
  4. Gerdes K, Wagner E. RNA antitoxins. Curr Opin Microbiol. 2007;10:117-24 pubmed
    ..Thus, it is possible that an ancestral antitoxin gene evolved into the present toxin gene (symE) whose translation is repressed by an RNA antitoxin (SymR). ..