Gene Symbol: moaB
Description: inactive molybdopterin adenylyltransferase
Alias: ECK0771, JW0765
Species: Escherichia coli str. K-12 substr. MG1655
McNicholas P, Rech S, Gunsalus R. Characterization of the ModE DNA-binding sites in the control regions of modABCD and moaABCDE of Escherichia coli. Mol Microbiol. 1997;23:515-24 pubmed
..These findings demonstrate that ModE acts both as a repressor and activator of the mod and moa operons, respectively, depending on the properties of the binding site. ..
Rieder C, Eisenreich W, O Brien J, Richter G, Götze E, Boyle P, et al
. Rearrangement reactions in the biosynthesis of molybdopterin--an NMR study with multiply 13C/15N labelled precursors. Eur J Biochem. 1998;255:24-36 pubmed
..Carbon atom C1' of compound Z is derived from carbon atom C8 of a guanine derivative. The remodeling of the carbon skeleton of the pentose and purine moieties proceed via intramolecular rearrangement reactions. ..
Bevers L, Hagedoorn P, Santamaria Araujo J, Magalon A, Hagen W, Schwarz G. Function of MoaB proteins in the biosynthesis of the molybdenum and tungsten cofactors. Biochemistry. 2008;47:949-56 pubmed publisher
..Here, we describe the function of the Pyrococcus furiosus MoaB protein that is homologous to bacterial (such as MogA) and eukaryotic proteins (such as Cnx1) involved in the final ..
Kozmin S, Schaaper R. Genetic characterization of moaB mutants of Escherichia coli. Res Microbiol. 2013;164:689-94 pubmed publisher
..However, the role of the moaB gene within this operon has remained enigmatic...
Shanmugam K, Stewart V, Gunsalus R, Boxer D, Cole J, Chippaux M, et al
. Proposed nomenclature for the genes involved in molybdenum metabolism in Escherichia coli and Salmonella typhimurium. Mol Microbiol. 1992;6:3452-4 pubmed
Rivers S, McNairn E, Blasco F, Giordano G, Boxer D. Molecular genetic analysis of the moa operon of Escherichia coli K-12 required for molybdenum cofactor biosynthesis. Mol Microbiol. 1993;8:1071-81 pubmed
..The moa locus is orientated clockwise at 17.7 minutes in the chromosome. ..
Bader G, Gomez Ortiz M, Haussmann C, Bacher A, Huber R, Fischer M. Structure of the molybdenum-cofactor biosynthesis protein MoaB of Escherichia coli. Acta Crystallogr D Biol Crystallogr. 2004;60:1068-75 pubmed
..The crystal structure of the MoaB protein from E. coli was determined by multiple anomalous dispersion at 2...
Sanishvili R, Beasley S, Skarina T, Glesne D, Joachimiak A, Edwards A, et al
. The crystal structure of Escherichia coli MoaB suggests a probable role in molybdenum cofactor synthesis. J Biol Chem. 2004;279:42139-46 pubmed
The crystal structure of Escherichia coli MoaB was determined by multiwavelength anomalous diffraction phasing and refined at 1.6-A resolution. The molecule displayed a modified Rossman fold...