Gene Symbol: mlaF
Description: ABC transporter maintaining OM lipid asymmetry, ATP-binding protein
Alias: ECK3184, JW3162, vpsA, yrbF
Species: Escherichia coli str. K-12 substr. MG1655

Top Publications

  1. Hong M, Gleason Y, Wyckoff E, Payne S. Identification of two Shigella flexneri chromosomal loci involved in intercellular spreading. Infect Immun. 1998;66:4700-10 pubmed
    ..Recombinant plasmids carrying the S. flexneri vpsA, -B, and -C genes complemented all of the phenotypes of the vpsC mutant...
  2. Malinverni J, Silhavy T. An ABC transport system that maintains lipid asymmetry in the gram-negative outer membrane. Proc Natl Acad Sci U S A. 2009;106:8009-14 pubmed publisher
    ..We propose that the Mla pathway constitutes a bacterial intermembrane PL trafficking system...
  3. Thong S, Ercan B, Torta F, Fong Z, Wong H, Wenk M, et al. Defining key roles for auxiliary proteins in an ABC transporter that maintains bacterial outer membrane lipid asymmetry. elife. 2016;5: pubmed publisher
    ..We establish that the transporter comprises canonical components, MlaF and MlaE, and auxiliary proteins, MlaD and MlaB, of previously unknown functions...