Gene Symbol: mdtH
Description: multidrug resistance efflux transporter conferring overexpression resistance to norfloxacin and enoxacin
Alias: ECK1050, JW1052, yceL
Species: Escherichia coli str. K-12 substr. MG1655

Top Publications

  1. Paulsen I, Nguyen L, Sliwinski M, Rabus R, Saier M. Microbial genome analyses: comparative transport capabilities in eighteen prokaryotes. J Mol Biol. 2000;301:75-100 pubmed
    ..Archaea and spirochetes exhibit fewer proteins with multiple transmembrane segments and fewer net transporters than most bacteria. These results provide insight into the relevance of transport to the overall physiology of prokaryotes. ..
  2. Vlamis Gardikas A, Aslund F, Spyrou G, Bergman T, Holmgren A. Cloning, overexpression, and characterization of glutaredoxin 2, an atypical glutaredoxin from Escherichia coli. J Biol Chem. 1997;272:11236-43 pubmed
    ..Grx2 being radically different from the presently known glutaredoxins in terms of molecular weight, amino acid sequence, catalytic activity, and lack of a consensus GSH-binding site is the first member of a novel class of glutaredoxins. ..
  3. Hirakawa H, Inazumi Y, Masaki T, Hirata T, Yamaguchi A. Indole induces the expression of multidrug exporter genes in Escherichia coli. Mol Microbiol. 2005;55:1113-26 pubmed
    ..found that indole induces a variety of xenobiotic exporter genes including acrD, acrE, cusB, emrK, mdtA, mdtE and yceL. Indole treatment of E...