Gene Symbol: mcbA
Description: colanic acid mucoidy stimulation protein
Alias: ECK0795, JW5106, ybiM
Species: Escherichia coli str. K-12 substr. MG1655

Top Publications

  1. Rudd K, Humphery Smith I, Wasinger V, Bairoch A. Low molecular weight proteins: a challenge for post-genomic research. Electrophoresis. 1998;19:536-44 pubmed publisher
    ..The problem of accurate protein sequence identification is not limited to small proteins or to E. coli; these problems are encountered to varying degrees throughout all sequence databases...
  2. McHugh J, Rodríguez Quiñones F, Abdul Tehrani H, Svistunenko D, Poole R, Cooper C, et al. Global iron-dependent gene regulation in Escherichia coli. A new mechanism for iron homeostasis. J Biol Chem. 2003;278:29478-86 pubmed
    ..In combination, the results provide compelling evidence for the regulation of intracellular iron consumption by the Fe2+-Fur complex. ..
  3. Zhang X, García Contreras R, Wood T. Escherichia coli transcription factor YncC (McbR) regulates colanic acid and biofilm formation by repressing expression of periplasmic protein YbiM (McbA). ISME J. 2008;2:615-31 pubmed publisher
    ..and gel shift assays demonstrated that YncC is a repressor of the predicted periplasmic protein-encoding gene, ybiM, which was corroborated by the isogenic yncC ybiM double mutation that repressed the yncC phenotypes (biofilm ..
  4. Dupuy F, Chirou M, de Arcuri B, Minahk C, Morero R. Proton motive force dissipation precludes interaction of microcin J25 with RNA polymerase, but enhances reactive oxygen species overproduction. Biochim Biophys Acta. 2009;1790:1307-13 pubmed publisher
    ..These results show the first evidence of the mechanism underlying ROS production in sensitive bacteria. ..
  5. Shkundina I, Serebryakova M, Severinov K. The C-terminal part of microcin B is crucial for DNA gyrase inhibition and antibiotic uptake by sensitive cells. J Bacteriol. 2014;196:1759-67 pubmed publisher
    ..The results highlight the importance of unmodified McB amino acids for function and open the way for creation of recombinant McB derivatives with an altered or expanded spectrum of antibacterial action. ..