Gene Symbol: malZ
Description: maltodextrin glucosidase
Alias: ECK0397, JW0393
Species: Escherichia coli str. K-12 substr. MG1655
Paul S, Punam S, Chaudhuri T. Chaperone-assisted refolding of Escherichia coli maltodextrin glucosidase. FEBS J. 2007;274:6000-10 pubmed
Peist R, Schneider Fresenius C, Boos W. The MalT-dependent and malZ-encoded maltodextrin glucosidase of Escherichia coli can be converted into a dextrinyltransferase by a single mutation. J Biol Chem. 1996;271:10681-9 pubmed
b>malZ is a member of the mal regulon. It is controlled by MatT, the transcriptional activator of the maltose system. MalZ has been purified and identified as an enzyme hydrolyzing maltotriose and longer maltodextrins to glucose and maltose...
Paul S, Chaudhuri T. Chaperone mediated solubilization of 69-kDa recombinant maltodextrin glucosidase in Escherichia coli. J Appl Microbiol. 2008;104:35-41 pubmed publisher
..coli. Our study could help in developing the strategy for enhancing the production of soluble industrial enzymes and finding the therapeutic agents against protein misfolding diseases. ..
Lucht J, Boos W, Bremer E. Alignment of genes from the 9-minute region (araJ to tsx) of the Escherichia coli K-12 linkage map to the physical map. J Bacteriol. 1992;174:1709-10 pubmed
Reuter K, Slany R, Ullrich F, Kersten H. Structure and organization of Escherichia coli genes involved in biosynthesis of the deazaguanine derivative queuine, a nutrient factor for eukaryotes. J Bacteriol. 1991;173:2256-64 pubmed
..The organization of the promoter sequences and the termination sites suggests that queA, tgt, and ORF 12 are localized on a putative operon together with the genes secD and secF. ..
Tapio S, Yeh F, Shuman H, Boos W. The malZ gene of Escherichia coli, a member of the maltose regulon, encodes a maltodextrin glucosidase. J Biol Chem. 1991;266:19450-8 pubmed
..The gene encoding the enzyme activity, referred to as malZ, is located at 9.3 min on the chromosomal map...
Dippel R, Bergmiller T, BOHM A, Boos W. The maltodextrin system of Escherichia coli: glycogen-derived endogenous induction and osmoregulation. J Bacteriol. 2005;187:8332-9 pubmed
..induction was dependent on the presence of MalP, maltodextrin phosphorylase, while expression was counteracted by MalZ, maltodextrin glucosidase. Glycogen-derived endogenous induction was sensitive to high osmolarity...
Paul S, Singh C, Mishra S, Chaudhuri T. The 69 kDa Escherichia coli maltodextrin glucosidase does not get encapsulated underneath GroES and folds through trans mechanism during GroEL/GroES-assisted folding. FASEB J. 2007;21:2874-85 pubmed
..coli protein maltodextrin glucosidase (MalZ). Coexpression of GroEL and GroES in E. coli causes a 2-fold enhancement of exogenous MalZ activity in vivo...
Paul S, Kundu M, Das K, Mishra S, Chaudhuri T. Unfolding studies of Escherichia coli maltodextrin glucosidase monitored by fluorescence spectroscopy. J Biol Phys. 2008;34:539-50 pubmed publisher
Equilibrium unfolding of a 69-kDa monomeric Escherichia coli maltodextrin glucosidase (MalZ) was studied using intrinsic and extrinsic fluorescence spectroscopy...