Gene Symbol: leuO
Description: leucine transcriptional activator
Species: Escherichia coli O157:H7 str. Sakai

Top Publications

  1. Fang M, Majumder A, Tsai K, Wu H. ppGpp-dependent leuO expression in bacteria under stress. Biochem Biophys Res Commun. 2000;276:64-70 pubmed publisher
    Despite the known potential transcription regulatory role of leuO gene product, LeuO, the condition when leuO expresses during bacterial growth cycle remains unclear...
  2. Chen C, Fang M, Majumder A, Wu H. A 72-base pair AT-rich DNA sequence element functions as a bacterial gene silencer. J Biol Chem. 2001;276:9478-85 pubmed
    We have previously demonstrated that sequential activation of the bacterial ilvIH-leuO-leuABCD gene cluster involves a promoter-relay mechanism...
  3. Takao M, Yen H, Tobe T. LeuO enhances butyrate-induced virulence expression through a positive regulatory loop in enterohaemorrhagic Escherichia coli. Mol Microbiol. 2014;93:1302-13 pubmed publisher
    ..Here, we show that expression of the leuO gene, which encodes a LysR-type transcriptional regulator, is enhanced by butyrate via Lrp, which is also necessary ..