ilvL

Summary

Gene Symbol: ilvL
Description: ilvG operon leader peptide
Alias: ECK3759, JW3739
Species: Escherichia coli str. K-12 substr. MG1655

Top Publications

  1. Lawther R, Wek R, Lopes J, Pereira R, Taillon B, Hatfield G. The complete nucleotide sequence of the ilvGMEDA operon of Escherichia coli K-12. Nucleic Acids Res. 1987;15:2137-55 pubmed
    ..This new information contributes to a more complete understanding of the overall control of the biosynthesis of isoleucine and valine...
  2. Sameshima J, Wek R, Hatfield G. Overlapping transcription and termination of the convergent ilvA and ilvY genes of Escherichia coli. J Biol Chem. 1989;264:1224-31 pubmed
    ..These experiments demonstrate that the converging transcripts from the ilvA and ilvY genes terminate in the coding region of the opposing gene. ..
  3. Driver R, Lawther R. Physical analysis of deletion mutations in the ilvGEDA operon of Escherichia coli K-12. J Bacteriol. 1985;162:598-606 pubmed
    ..This genomic analysis demonstrates that the ilv restriction site map that was established previously by the analysis of recombinant bacteriophage and plasmids is identical to that on the genome. ..
  4. Ortuno M, Lawther R. Effect of the deletion of upstream DNA sequences on expression from the ilvGp2 promoter of the ilvGMEDA operon of Escherichia coli K-12. Nucleic Acids Res. 1987;15:1521-42 pubmed
    ..Analysis of products of transcription in vitro indicates that the effects observed in vivo are probably not due to DNA conformation or interactions of RNA polymerase. ..
  5. Taillon M, Gotto D, Lawther R. The DNA sequence of the promoter-attenuator of the ilvGEDA operon of Salmonella typhimurium. Nucleic Acids Res. 1981;9:3419-32 pubmed
    ..DNA sequence analysis shows only seven base pair differences exist between the DNA sequence of the ilvGEDA promoter-attenuator of S. typhimurium and that previously published for Escherichia coli K12...
  6. Lawther R, Calhoun D, Adams C, Hauser C, Gray J, Hatfield G. Molecular basis of valine resistance in Escherichia coli K-12. Proc Natl Acad Sci U S A. 1981;78:922-5 pubmed
  7. Parekh B, Hatfield G. Growth rate-related regulation of the ilvGMEDA operon of Escherichia coli K-12 is a consequence of the polar frameshift mutation in the ilvG gene of this strain. J Bacteriol. 1997;179:2086-8 pubmed
    ..Thus, the growth rate-related expression of the ilvGMEDA operon in E. coli K-12 is the fortuitous consequence of the polar frameshift mutation in the ilvG gene of this strain. ..
  8. Vyazmensky M, Zherdev Y, Slutzker A, Belenky I, Kryukov O, Barak Z, et al. Interactions between large and small subunits of different acetohydroxyacid synthase isozymes of Escherichia coli. Biochemistry. 2009;48:8731-7 pubmed publisher
    ..We suggest hypotheses for the mechanism of valine inhibition, and reject one involving induced dissociation of subunits. ..
  9. Harms E, Hsu J, Subrahmanyam C, Umbarger H. Comparison of the regulatory regions of ilvGEDA operons from several enteric organisms. J Bacteriol. 1985;164:207-16 pubmed
    ..In both organisms, that single leucine codon is the rarely used CUA rather than the CUG that is in E. coli, S. typhimurium, and K. aerogenes. ..

More Information

Publications11

  1. Lawther R, Hatfield G. Multivalent translational control of transcription termination at attenuator of ilvGEDA operon of Escherichia coli K-12. Proc Natl Acad Sci U S A. 1980;77:1862-6 pubmed
    ..The mutually exclusive secondary structures of the leader RNA have been analyzed. On the basis of these data, a model for the multivalent attenuation of the ilvGEDA operon is proposed. ..
  2. Nargang F, Subrahmanyam C, Umbarger H. Nucleotide sequence of ilvGEDA operon attenuator region of Escherichia coli. Proc Natl Acad Sci U S A. 1980;77:1823-7 pubmed
    ..In vitro transcription experiments yielded a transcript of about 183 nucelotides, compatible with the predictions of the model. ..