hokE

Summary

Gene Symbol: hokE
Description: toxic polypeptide, small
Alias: ECK0574, JW5084, ybdY
Species: Escherichia coli str. K-12 substr. MG1655

Top Publications

  1. Gerdes K, Gultyaev A, Franch T, Pedersen K, Mikkelsen N. Antisense RNA-regulated programmed cell death. Annu Rev Genet. 1997;31:1-31 pubmed
    ..The complex phylogenetic relationships of the plasmid- and chromosome-encoded systems are also presented and discussed. ..
  2. Pedersen K, Gerdes K. Multiple hok genes on the chromosome of Escherichia coli. Mol Microbiol. 1999;32:1090-102 pubmed
    ..e. hokA, hokC and hokE), one system is probably inactivated by point mutation (hokB), whereas the fifth system is inactivated by a major ..
  3. Fernandez de Henestrosa A, Ogi T, Aoyagi S, Chafin D, Hayes J, Ohmori H, et al. Identification of additional genes belonging to the LexA regulon in Escherichia coli. Mol Microbiol. 2000;35:1560-72 pubmed
    ..These experiments have allowed us to identify seven new LexA-regulated genes, thus bringing the present number of genes in the E. coli LexA regulon to 31. The potential function of each newly identified LexA-regulated gene is discussed. ..
  4. Gerdes K, Wagner E. RNA antitoxins. Curr Opin Microbiol. 2007;10:117-24 pubmed
    ..Thus, it is possible that an ancestral antitoxin gene evolved into the present toxin gene (symE) whose translation is repressed by an RNA antitoxin (SymR). ..
  5. Rudd K, Humphery Smith I, Wasinger V, Bairoch A. Low molecular weight proteins: a challenge for post-genomic research. Electrophoresis. 1998;19:536-44 pubmed publisher
    ..The problem of accurate protein sequence identification is not limited to small proteins or to E. coli; these problems are encountered to varying degrees throughout all sequence databases...
  6. Faridani O, Nikravesh A, Pandey D, Gerdes K, Good L. Competitive inhibition of natural antisense Sok-RNA interactions activates Hok-mediated cell killing in Escherichia coli. Nucleic Acids Res. 2006;34:5915-22 pubmed
    ..Therefore, it is possible to activate suicide in bacteria by targeting antitoxins. ..