higB

Summary

Gene Symbol: higB
Description: mRNA interferase toxin of the HigB-HigA toxin-antitoxin system
Alias: ECK3073, JW3054, ygjN
Species: Escherichia coli str. K-12 substr. MG1655

Top Publications

  1. Christensen Dalsgaard M, Jørgensen M, Gerdes K. Three new RelE-homologous mRNA interferases of Escherichia coli differentially induced by environmental stresses. Mol Microbiol. 2010;75:333-48 pubmed publisher
    ..coli. We found that the yafNO, higBA (ygjNM) and ygiUT loci encode mRNA interferases related to RelE. YafO and HigB cleaved translated mRNA only, while YgiU cleaved RNA site-specifically at GC[A/U], independently of translation...