glutaredoxin 3

Summary

Gene Symbol: glutaredoxin 3
Description: glutaredoxin 3
Species: Escherichia coli O157:H7 str. Sakai

Top Publications

  1. Aslund F, Ehn B, Miranda Vizuete A, Pueyo C, Holmgren A. Two additional glutaredoxins exist in Escherichia coli: glutaredoxin 3 is a hydrogen donor for ribonucleotide reductase in a thioredoxin/glutaredoxin 1 double mutant. Proc Natl Acad Sci U S A. 1994;91:9813-7 pubmed
    ..The physiological functions of Grx2 and Grx3 remain to be determined. ..
  2. Nordstrand K, slund F, Holmgren A, Otting G, Berndt K. NMR structure of Escherichia coli glutaredoxin 3-glutathione mixed disulfide complex: implications for the enzymatic mechanism. J Mol Biol. 1999;286:541-52 pubmed
    ..A comparison of glutathione binding in Grx3-SG and ligand binding in other members of the thioredoxin superfamily is presented, which illustrates the highly conserved intermolecular interactions in this protein family. ..
  3. Aslund F, Nordstrand K, Berndt K, Nikkola M, Bergman T, Ponstingl H, et al. Glutaredoxin-3 from Escherichia coli. Amino acid sequence, 1H AND 15N NMR assignments, and structural analysis. J Biol Chem. 1996;271:6736-45 pubmed
    ..Thus, despite an identical active site disulfide motif and a similar secondary structure and tertiary fold, Grx3 and Grx1 display large functional differences in in vitro protein disulfide oxido-reduction reactions. ..
  4. Nordstrand K, Sandstrom A, Aslund F, Holmgren A, Otting G, Berndt K. NMR structure of oxidized glutaredoxin 3 from Escherichia coli. J Mol Biol. 2000;303:423-32 pubmed
    A high precision NMR structure of oxidized glutaredoxin 3 [C65Y] from Escherichia coli has been determined...