glutaredoxin 2


Gene Symbol: glutaredoxin 2
Description: glutaredoxin
Species: Escherichia coli O157:H7 str. Sakai

Top Publications

  1. Aslund F, Ehn B, Miranda Vizuete A, Pueyo C, Holmgren A. Two additional glutaredoxins exist in Escherichia coli: glutaredoxin 3 is a hydrogen donor for ribonucleotide reductase in a thioredoxin/glutaredoxin 1 double mutant. Proc Natl Acad Sci U S A. 1994;91:9813-7 pubmed
    ..The physiological functions of Grx2 and Grx3 remain to be determined. ..
  2. Xia B, Vlamis Gardikas A, Holmgren A, Wright P, Dyson H. Solution structure of Escherichia coli glutaredoxin-2 shows similarity to mammalian glutathione-S-transferases. J Mol Biol. 2001;310:907-18 pubmed publisher
    b>Glutaredoxin 2 (Grx2) from Escherichia coli is distinguished from other glutaredoxins by its larger size, low overall sequence identity and lack of electron donor activity with ribonucleotide reductase...
  3. Vlamis Gardikas A, Aslund F, Spyrou G, Bergman T, Holmgren A. Cloning, overexpression, and characterization of glutaredoxin 2, an atypical glutaredoxin from Escherichia coli. J Biol Chem. 1997;272:11236-43 pubmed
    b>Glutaredoxin 2 (Grx2) from Escherichia coli catalyzes GSH-disulfide oxidoreductions via two redox-active cysteine residues, but in contrast to glutaredoxin 1 (Grx1) and glutaredoxin 3 (Grx3), is not a hydrogen donor for ribonucleotide ..