Gene Symbol: ECs4441
Description: major cold shock protein
Species: Escherichia coli O157:H7 str. Sakai

Top Publications

  1. Feng W, Tejero R, Zimmerman D, Inouye M, Montelione G. Solution NMR structure and backbone dynamics of the major cold-shock protein (CspA) from Escherichia coli: evidence for conformational dynamics in the single-stranded RNA-binding site. Biochemistry. 1998;37:10881-96 pubmed publisher
    ..88 +/- 0.04 ns and provide evidence for fast time scale (taue < 500 ps) dynamics in surface loops and motions on the microsecond to millisecond time scale within the proposed nucleic acid-binding epitope...
  2. Goldstein J, Pollitt N, Inouye M. Major cold shock protein of Escherichia coli. Proc Natl Acad Sci U S A. 1990;87:283-7 pubmed
    ..We have cloned the gene encoding this protein and have completed the nucleotide sequence analysis, which revealed that the gene encodes a hydrophilic protein of 70 amino acid residues...
  3. Newkirk K, Feng W, Jiang W, Tejero R, Emerson S, Inouye M, et al. Solution NMR structure of the major cold shock protein (CspA) from Escherichia coli: identification of a binding epitope for DNA. Proc Natl Acad Sci U S A. 1994;91:5114-8 pubmed
    ..These isotope-edited pulsed-field gradient NMR data provide a low-resolution mapping of a DNA-binding epitope on CspA...