Gene Symbol: ECs4375
Description: arsenate reductase
Species: Escherichia coli O157:H7 str. Sakai

Top Publications

  1. Rosen B. The plasmid-encoded arsenical resistance pump: an anion-translocating ATPase. Res Microbiol. 1990;141:336-41 pubmed
    ..This two-subunit enzyme produces resistance to arsenite and antimonite. A third gene, arsC, expands the substrate specificity to allow for arsenate pumping and resistance. ..
  2. Rosen B, Weigel U, Monticello R, Edwards B. Molecular analysis of an anion pump: purification of the ArsC protein. Arch Biochem Biophys. 1991;284:381-5 pubmed
    ..The arsC gene was cloned behind a strong promoter and expressed at high levels. The ArsC protein was purified and crystallized. ..
  3. Chen C, Misra T, Silver S, Rosen B. Nucleotide sequence of the structural genes for an anion pump. The plasmid-encoded arsenical resistance operon. J Biol Chem. 1986;261:15030-8 pubmed
    ..A model is proposed in which these gene products form an anion translocating ATPase for extrusion of arsenite and arsenate from resistant cells. ..
  4. Bruhn D, Li J, Silver S, Roberto F, Rosen B. The arsenical resistance operon of IncN plasmid R46. FEMS Microbiol Lett. 1996;139:149-53 pubmed
    ..The R46 system contains only the second known versions of arsA and arsD, after those of plasmid R773. Western blot analysis identified the R46 proteins using antibodies against R773 ArsA, ArsD and ArsR. ..