Gene Symbol: ECs0068
Description: AraC family transcriptional regulator
Species: Escherichia coli O157:H7 str. Sakai

Top Publications

  1. Hendrickson W, Stoner C, Schleif R. Characterization of the Escherichia coli araFGH and araJ promoters. J Mol Biol. 1990;215:497-510 pubmed
    ..Two CRP sites were observed; one is upstream from the AraC site and one is downstream from the transcription start site. ..
  2. Cass L, Horwitz A, Miyada C, Greenfield L, Wilcox G. The araC regulatory gene mRNA contains a leader sequence. Mol Gen Genet. 1980;180:219-26 pubmed
    ..Plasmids which contained a functional araC gene were identified by genetic complementation tests. DNA sequence analysis of the promoter-proximal region of the araC gene revealed that araC mRNA contains a 150 nucleotide leader. ..
  3. Wallace R, Lee N, Fowler A. The araC gene of Escherichia coli: transcriptional and translational start-points and complete nucleotide sequence. Gene. 1980;12:179-90 pubmed
    ..There is, therefore, a leader sequence of 164 bp preceding the araC gene. ..
  4. Soisson S, MacDougall Shackleton B, Schleif R, Wolberger C. Structural basis for ligand-regulated oligomerization of AraC. Science. 1997;276:421-5 pubmed
    ..The ligand-gated oligomerization as seen in AraC provides the basis of a plausible mechanism for modulating the protein's DNA-looping properties. ..
  5. Johnson C, Schleif R. In vivo induction kinetics of the arabinose promoters in Escherichia coli. J Bacteriol. 1995;177:3438-42 pubmed
    ..5, 5, and 1, respectively. These results provide a basis for subsequent studies to determine the mechanism(s) by which AraC protein activates transcription from the different arabinose promoters. ..
  6. Soisson S, MacDougall Shackleton B, Schleif R, Wolberger C. The 1.6 A crystal structure of the AraC sugar-binding and dimerization domain complexed with D-fucose. J Mol Biol. 1997;273:226-37 pubmed