Gene Symbol: eamA
Description: cysteine and O-acetyl-L-serine efflux system
Alias: ECK1526, JW5250, ydeD
Species: Escherichia coli str. K-12 substr. MG1655

Top Publications

  1. Cohen S, H chler H, Levy S. Genetic and functional analysis of the multiple antibiotic resistance (mar) locus in Escherichia coli. J Bacteriol. 1993;175:1484-92 pubmed
    ..The function of ORF72, designated marB, encoding the third putative protein in the operon, and that of other ORFs detected within the 7.8-kb fragment have not yet been determined...
  2. Franke I, Resch A, Dassler T, Maier T, Bock A. YfiK from Escherichia coli promotes export of O-acetylserine and cysteine. J Bacteriol. 2003;185:1161-6 pubmed
    ..did not show any phenotype, and it exported O-acetylserine and cysteine when transformed with a plasmid carrying ydeD, a previously characterized, alternate O-acetylserine/cysteine exporter...
  3. Yamada S, Awano N, Inubushi K, Maeda E, Nakamori S, Nishino K, et al. Effect of drug transporter genes on cysteine export and overproduction in Escherichia coli. Appl Environ Microbiol. 2006;72:4735-42 pubmed
    ..The use of an L-cysteine efflux system could be promising for breeding L-cysteine overproducers. In addition to YdeD and YfiK, which have been reported previously as L-cysteine exporter proteins in E...
  4. Dassler T, Maier T, Winterhalter C, Bock A. Identification of a major facilitator protein from Escherichia coli involved in efflux of metabolites of the cysteine pathway. Mol Microbiol. 2000;36:1101-12 pubmed
    ..The results indicate that orf299 codes for an export pump for different metabolites of the cysteine pathway. Its relation to other efflux systems and the physiological role are discussed. ..
  5. Pittman M, Corker H, Wu G, Binet M, Moir A, Poole R. Cysteine is exported from the Escherichia coli cytoplasm by CydDC, an ATP-binding cassette-type transporter required for cytochrome assembly. J Biol Chem. 2002;277:49841-9 pubmed
    ..We propose that CydDC exports cysteine, crucial for redox homeostasis in the periplasm...