Gene Symbol: cysD
Description: sulfate adenylyltransferase, subunit 2
Alias: ECK2747, JW2722
Species: Escherichia coli str. K-12 substr. MG1655

Top Publications

  1. Leyh T, Vogt T, Suo Y. The DNA sequence of the sulfate activation locus from Escherichia coli K-12. J Biol Chem. 1992;267:10405-10 pubmed
    ..The sequence includes the structural genes encoding the enzymes ATP sulfurylase (cysD and cysN) and APS kinase (cysC) which catalyze the synthesis of activated sulfate...
  2. Tei H, Murata K, Kimura A. Molecular cloning of the cys genes (cysC, cysD, cysH, cysI, cysJ, and cysG) responsible for cysteine biosynthesis in Escherichia coli K-12. Biotechnol Appl Biochem. 1990;12:212-6 pubmed
    ..The following results were obtained. First, the cysCDHIJ regulon could be separated into cysCD and cysHIJ regions. Second, the cysG gene was quite different from the cysI and cysJ genes. ..
  3. Malo M, Loughlin R. Promoter elements and regulation of expression of the cysD gene of Escherichia coli K-12. Gene. 1990;87:127-31 pubmed
    The cysD gene, involved in cysteine biosynthesis in Escherichia coli and Salmonella typhimurium, is positively regulated by the CysB regulatory protein. The cysD promoter of E. coli K-12 in a 492-bp PstI-Eco RI fragment was sequenced...
  4. Leyh T, Taylor J, Markham G. The sulfate activation locus of Escherichia coli K12: cloning, genetic, and enzymatic characterization. J Biol Chem. 1988;263:2409-16 pubmed
    ..Overproduction of ATP sulfurylase requires the expression of both the cysD gene, encoding a 27-kDa polypeptide, and a previously unidentified gene, denoted cysN, which encodes a 62-kDa ..
  5. Hunt C, Colless V, Smith M, Molasky D, Malo M, Loughlin R. Lambda transducing phage and clones carrying genes of the cysJIHDC gene cluster of Escherichia coli K12. J Gen Microbiol. 1987;133:2707-17 pubmed
    ..Cysteine regulation of the cloned cysJ and cysD genes was shown as well as cysteine regulation of beta-galactosidase in some constructs...
  6. Leyh T. On the advantages of imperfect energetic linkage. Methods Enzymol. 1999;308:48-70 pubmed