Gene Symbol: betI
Description: choline-inducible betIBA-betT divergent operon transcriptional repressor
Alias: ECK0311, JW0305
Species: Escherichia coli str. K-12 substr. MG1655
Lamark T, Røkenes T, McDougall J, Strøm A. The complex bet promoters of Escherichia coli: regulation by oxygen (ArcA), choline (BetI), and osmotic stress. J Bacteriol. 1996;178:1655-62 pubmed
..It comprises a regulatory gene, betI, and three structural genes: betT (choline porter), betA (choline dehydrogenase), and betB (betaine aldehyde ..
Rkenes T, Lamark T, Strøm A. DNA-binding properties of the BetI repressor protein of Escherichia coli: the inducer choline stimulates BetI-DNA complex formation. J Bacteriol. 1996;178:1663-70 pubmed
..In an accompanying paper we report that the betT and betI promoters are divergently organized and partially overlapping and that both are negatively regulated by BetI in ..
Lamark T, Kaasen I, Eshoo M, Falkenberg P, McDougall J, Strøm A. DNA sequence and analysis of the bet genes encoding the osmoregulatory choline-glycine betaine pathway of Escherichia coli. Mol Microbiol. 1991;5:1049-64 pubmed
..The bet genes are tightly spaced, with betT located upstream of, and transcribed divergently to, the tandemly linked betIBA genes. ..
Ramos J, Martínez Bueno M, Molina Henares A, Teran W, Watanabe K, Zhang X, et al
. The TetR family of transcriptional repressors. Microbiol Mol Biol Rev. 2005;69:326-56 pubmed
..Information related to the TetR family of regulators has been updated in a database that can be accessed at www.bactregulators.org. ..
Krishna S, Andersson A, Semsey S, Sneppen K. Structure and function of negative feedback loops at the interface of genetic and metabolic networks. Nucleic Acids Res. 2006;34:2455-62 pubmed
..We use three examples, the bet, mer and lac systems in Escherichia coli, to illustrate the behaviour of such feedback loops. ..