Gene Symbol: argO
Description: arginine transporter
Alias: ECK2919, JW2890, yggA
Species: Escherichia coli str. K-12 substr. MG1655
Laishram R, Gowrishankar J. Environmental regulation operating at the promoter clearance step of bacterial transcription. Genes Dev. 2007;21:1258-72 pubmed
In vivo transcription of the Escherichia coli argO gene, which encodes an arginine (Arg) exporter, requires the LysR-family regulator protein ArgP (previously called IciA) and is induced in the presence of Arg or its naturally occurring ..
Aleshin V, Zakataeva N, Livshits V. A new family of amino-acid-efflux proteins. Trends Biochem Sci. 1999;24:133-5 pubmed
Vrljic M, Garg J, Bellmann A, Wachi S, Freudl R, Malecki M, et al
. The LysE superfamily: topology of the lysine exporter LysE of Corynebacterium glutamicum, a paradyme for a novel superfamily of transmembrane solute translocators. J Mol Microbiol Biotechnol. 1999;1:327-36 pubmed
..Functionally characterized members of the LysE superfamily export L-lysine, cadmium and possibly quarternary amines. We suggest that LysE superfamily members will prove to catalyze export of a variety of biologically important solutes. ..
Alefounder P, Perham R. Identification, molecular cloning and sequence analysis of a gene cluster encoding the class II fructose 1,6-bisphosphate aldolase, 3-phosphoglycerate kinase and a putative second glyceraldehyde 3-phosphate dehydrogenase of Escherichia coli. Mol Microbiol. 1989;3:723-32 pubmed
..coli and which maps elsewhere on the chromosome. The products, if any, of several other open reading frames remain to be identified. ..
Peeters E, Nguyen Le Minh P, Foulquié Moreno M, Charlier D. Competitive activation of the Escherichia coli argO gene coding for an arginine exporter by the transcriptional regulators Lrp and ArgP. Mol Microbiol. 2009;74:1513-26 pubmed publisher
In vivo and in vitro analyses indicate that transcription of the argO gene coding for an arginine exporter is regulated by the global transcriptional regulator Lrp, an effect that went by unnoticed in previous genome-scale screenings of ..
Pathania A, Gupta A, Dubey S, Gopal B, Sardesai A. The Topology of the l-Arginine Exporter ArgO Conforms to an Nin-Cout Configuration in Escherichia coli: Requirement for the Cytoplasmic N-Terminal Domain, Functional Helical Interactions, and an Aspartate Pair for ArgO Function. J Bacteriol. 2016;198:3186-3199 pubmed
b>ArgO and LysE are members of the LysE family of exporter proteins and ordinarily mediate the export of l-arginine (Arg) in Escherichia coli and l-lysine (Lys) and Arg in Corynebacterium glutamicum, respectively...
Nandineni M, Gowrishankar J. Evidence for an arginine exporter encoded by yggA (argO) that is regulated by the LysR-type transcriptional regulator ArgP in Escherichia coli. J Bacteriol. 2004;186:3539-46 pubmed
..Our results suggest that yggA encodes an ArgP-regulated arginine exporter, and we have accordingly renamed it argO (for "arginine outward transport")...