Gene Symbol: cp
Description: coat protein
Species: Enterobacteria phage MS2
Min Jou W, Haegeman G, Ysebaert M, Fiers W. Nucleotide sequence of the gene coding for the bacteriophage MS2 coat protein. Nature. 1972;237:82-8 pubmed
Shtatland T, Gill S, Javornik B, Johansson H, Singer B, Uhlenbeck O, et al
. Interactions of Escherichia coli RNA with bacteriophage MS2 coat protein: genomic SELEX. Nucleic Acids Res. 2000;28:E93 pubmed
..Such methods may be useful tools for both randomized sequence SELEX and genomic SELEX...
Berzin V, Borisova G, Cielens I, Gribanov V, Jansone I, Rosenthal G, et al
. The regulatory region of MS2 phage RNA replicase cistron. Functional activity of individual MS2 RNA fragments. J Mol Biol. 1978;119:101-31 pubmed
Kastelein R, Remaut E, Fiers W, van Duin J. Lysis gene expression of RNA phage MS2 depends on a frameshift during translation of the overlapping coat protein gene. Nature. 1982;295:35-41 pubmed
..The out-of-phase fraction of ribosomes terminates at either one of two nonsense codons just preceding the lysis cistron. Termination is followed by initiation at the start codon of the lysis protein message. ..
Keef T, Wardman J, Ranson N, Stockley P, Twarock R. Structural constraints on the three-dimensional geometry of simple viruses: case studies of a new predictive tool. Acta Crystallogr A. 2013;69:140-50 pubmed publisher
..It can moreover be used as a basis for models of virus function, e.g. to characterize the start and end configurations of a structural transition important for infection. ..
Persson M, Tars K, Liljas L. PRR1 coat protein binding to its RNA translational operator. Acta Crystallogr D Biol Crystallogr. 2013;69:367-72 pubmed publisher
..The arrangement of the nucleotide bases in the loop of the stem-loop is different, leading to a difference in the stacking at the conserved Tyr86, which is equivalent to Tyr85 in MS2. ..
Beremand M, Blumenthal T. Overlapping genes in RNA phage: a new protein implicated in lysis. Cell. 1979;18:257-66 pubmed
Elsawy K, Caves L, Twarock R. The impact of viral RNA on the association rates of capsid protein assembly: bacteriophage MS2 as a case study. J Mol Biol. 2010;400:935-47 pubmed publisher
..The presence of the RNA hence dramatically decreases the number of dominant assembly pathways and thereby reduces the complexity of the self-assembly process of these viruses...