AHR

Summary

Gene Symbol: AHR
Description: aryl hydrocarbon receptor
Alias: AHR1, aryl hydrocarbon receptor, AhR 1, aryl hydrocarbon receptor 1
Species: duck

Top Publications

  1. Karchner S, Kennedy S, Trudeau S, Hahn M. Towards molecular understanding of species differences in dioxin sensitivity: initial characterization of Ah receptor cDNAs in birds and an amphibian. Mar Environ Res. 2000;50:51-6 pubmed
    ..Toxicol. Appl. Pharmacol., 141, 214-230]. Differences in the characteristics or expression of the aryl hydrocarbon receptor (AHR) could contribute to these species differences in PHAH responsiveness...
  2. Karchner S, Franks D, Kennedy S, Hahn M. The molecular basis for differential dioxin sensitivity in birds: role of the aryl hydrocarbon receptor. Proc Natl Acad Sci U S A. 2006;103:6252-7 pubmed publisher
    ..The mechanism of HAH toxicity involves altered gene expression subsequent to activation of the aryl hydrocarbon receptor (AHR), a basic helix-loop-helix-PAS transcription factor...
  3. Head J, Hahn M, Kennedy S. Key amino acids in the aryl hydrocarbon receptor predict dioxin sensitivity in avian species. Environ Sci Technol. 2008;42:7535-41 pubmed
    ..A recent study suggests that the amino acid residues corresponding to Ile324 and Ser380 in the chicken aryl hydrocarbon receptor 1 (AHR1) are important determinants of differential biochemical responses to 2,3,7,8-tetrachlorodibenzo-p-..