Genomes and Genes

Abcb1

Summary

Gene Symbol: Abcb1
Description: ATP binding cassette subfamily B member 1
Alias: multidrug resistance protein 1, MDR1-like/ABCB1-like, multidrug resistance protein 1-like protein
Species: Domestic guinea pig

Top Publications

  1. Hasibu I, Patoine D, Pilote S, Drolet B, Simard C. The guinea-pig expresses functional CYP2C and P-glycoprotein: further validation of its usefulness in drug biotransformation/transport studies. Biopharm Drug Dispos. 2015;36:183-203 pubmed publisher
    ..To further study both P-gp and CYP2C functional activities, the guinea-pig ABCB1/MDR1 and CYP2C genes were cloned...
  2. Iqbal M, Baello S, Javam M, Audette M, Gibb W, Matthews S. Regulation of Multidrug Resistance P-Glycoprotein in the Developing Blood-Brain Barrier: Interplay between Glucocorticoids and Cytokines. J Neuroendocrinol. 2016;28:12360 pubmed publisher
    P-glycoprotein (P-gp) encoded by Abcb1 provides protection to the developing brain from xenobiotics...