Gene Symbol: MMP13
Description: matrix metallopeptidase 13
Alias: collagenase 3, matrix metalloproteinase-13
Species: dog
Products:     MMP13

Top Publications

  1. Choi E, Lee J, Baek S, Kim S. Gene expression profile altered by orthodontic tooth movement during healing of surgical alveolar defect. Am J Orthod Dentofacial Orthop. 2017;151:1107-1115 pubmed publisher
    ..The genes participating in high woven-bone fraction in group DT6 could be identified as TNFSF11, MMP13, SPP1, and DMP1, which were verified by quantitative real-time polymerase chain reactions...
  2. Campbell S, Sood A, Argyle D, Nasir L, Argyle S, Bennett D. The cloning and functional analysis of canine matrix metalloproteinase-13 gene promoter. Gene. 2002;286:233-40 pubmed
    ..The canine MMP-13 promoter activity has also been compared to the basal and induced activity of the canine MMP-9, gelatinase B promoter in these cell types. ..
  3. Hellman N, Spector J, Robinson J, Zuo X, Saunier S, Antignac C, et al. Matrix metalloproteinase 13 (MMP13) and tissue inhibitor of matrix metalloproteinase 1 (TIMP1), regulated by the MAPK pathway, are both necessary for Madin-Darby canine kidney tubulogenesis. J Biol Chem. 2008;283:4272-82 pubmed
    ..Of the 19 MMPs and 3 TIMPs present on the Canine Genome 2.0 Array, MMP13 and TIMP1 were up-regulated 198- and 169-fold, respectively, via the MAPK pathway...
  4. Boileau C, Martel Pelletier J, Caron J, Msika P, Guillou G, Baudouin C, et al. Protective effects of total fraction of avocado/soybean unsaponifiables on the structural changes in experimental dog osteoarthritis: inhibition of nitric oxide synthase and matrix metalloproteinase-13. Arthritis Res Ther. 2009;11:R41 pubmed publisher
    ..This effect appears to be mediated through the inhibition of inducible nitric oxide synthase and MMP-13, which are key mediators of the structural changes that take place in osteoarthritis. ..