XBP1

Summary

Gene Symbol: XBP1
Description: X-box binding protein 1
Alias: XBPP1, X-box-binding protein 1, X-box binding protein pseudogene 1, XBP-1
Species: cow
Products:     XBP1

Top Publications

  1. Liu L, Qi X, Chen Z, Shaw L, Cai J, Smith L, et al. Targeting the IRE1?/XBP1 and ATF6 arms of the unfolded protein response enhances VEGF blockade to prevent retinal and choroidal neovascularization. Am J Pathol. 2013;182:1412-24 pubmed publisher
    ..In conclusion, activation of the UPR sustains angiogenesis by preventing degradation of intracellular VEGF. The IRE1?/ATF6 arms of the UPR offer a potential therapeutic target in the treatment of pathological angiogenesis...