GPBAR1

Summary

Gene Symbol: GPBAR1
Description: G protein-coupled bile acid receptor 1
Alias: TGR5, G-protein coupled bile acid receptor 1, G protein-coupled receptor TGR5
Species: cow

Top Publications

  1. Kawamata Y, Fujii R, Hosoya M, Harada M, Yoshida H, Miwa M, et al. A G protein-coupled receptor responsive to bile acids. J Biol Chem. 2003;278:9435-40 pubmed publisher
    ..We found that a novel G protein-coupled receptor, TGR5, is responsive to bile acids as a cell-surface receptor...
  2. Kida T, Tsubosaka Y, Hori M, Ozaki H, Murata T. Bile acid receptor TGR5 agonism induces NO production and reduces monocyte adhesion in vascular endothelial cells. Arterioscler Thromb Vasc Biol. 2013;33:1663-9 pubmed publisher
    b>TGR5 is a G-protein-coupled receptor for bile acids. So far, little is known about the function of TGR5 in vascular endothelial cells. ..