FGFR3

Summary

Gene Symbol: FGFR3
Description: fibroblast growth factor receptor 3
Alias: fibroblast growth factor receptor 3, fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism)
Species: cow
Products:     FGFR3

Top Publications

  1. Takami M, Yoneda K, Kobayashi Y, Moritomo Y, Kata S, Womack J, et al. The bovine fibroblast growth factor receptor 3 (FGFR3) gene is not the locus responsible for bovine chondrodysplastic dwarfism in Japanese brown cattle. Anim Genet. 2002;33:351-5 pubmed
    b>Fibroblast growth factor receptor 3 (FGFR3) is one of the four distinct membrane-spanning tyrosine kinase receptors for fibroblast growth factors...
  2. Campos D, Papa P, Marques J, Garbelotti F, Fátima L, Artoni L, et al. Somatic cell nuclear transfer is associated with altered expression of angiogenic factor systems in bovine placentomes at term. Genet Mol Res. 2010;9:309-23 pubmed publisher
    ..Alterations in the expression of VEGF-A and bFGF systems suggest that angiogenic factors are involved in abnormal placental development in cloned gestations, contributing to impaired fetal development and poor survival rates. ..
  3. Degnin C, Laederich M, Horton W. Ligand activation leads to regulated intramembrane proteolysis of fibroblast growth factor receptor 3. Mol Biol Cell. 2011;22:3861-73 pubmed publisher
    b>Fibroblast growth factor receptor 3 (FGFR3) is a major negative regulator of bone growth that inhibits the proliferation and differentiation of growth plate chondrocytes...