Genomes and Genes




Gene Symbol: FFAR1
Description: free fatty acid receptor 1
Alias: free fatty acid receptor 1
Species: cow

Top Publications

  1. Manosalva C, Mena J, Velasquez Z, Colenso C, Brauchi S, Burgos R, et al. Cloning, identification and functional characterization of bovine free fatty acid receptor-1 (FFAR1/GPR40) in neutrophils. PLoS ONE. 2015;10:e0119715 pubmed publisher
    Long chain fatty acids (LCFAs), which are ligands for the G-protein coupled receptor FFAR1 (GPR40), are increased in cow plasma after parturition, a period in which they are highly susceptible to infectious diseases...
  2. Mena S, Manosalva C, Carretta M, Teuber S, Olmo I, Burgos R, et al. Differential free fatty acid receptor-1 (FFAR1/GPR40) signalling is associated with gene expression or gelatinase granule release in bovine neutrophils. Innate Immun. 2016;22:479-89 pubmed publisher
    ..up-regulation of cyclooxygenase-2 (COX-2) and IL-8, as well as matrix metalloproteinase (MMP)-9 granule release in FFAR1/GPR40 agonist-stimulated neutrophils...

Scientific Experts