Research Topics

Genomes and Genes




Gene Symbol: FECH
Description: ferrochelatase
Alias: ferrochelatase, mitochondrial, heme synthase, heme synthetase, protoheme ferro-lyase, protoporphyria
Species: cow
Products:     FECH

Top Publications

  1. Brenner D, Frasier F. Cloning of murine ferrochelatase. Proc Natl Acad Sci U S A. 1991;88:849-53 pubmed
    ..The activity of ferrochelatase is deficient in the inherited disease protoporphyria. In this study, murine ferrochelatase cDNAs were obtained by screening cDNA libraries with an oligonucleotide ..
  2. Taketani S, Nakahashi Y, Osumi T, Tokunaga R. Molecular cloning, sequencing, and expression of mouse ferrochelatase. J Biol Chem. 1990;265:19377-80 pubmed
    ..The band pattern of the RNA of the mouse liver was the same as that of the MEL cells. Based on these results, we deduce that ferrochelatase in erythroid and hepatic cells can be only of one type. ..
  3. Shibuya H, Nonneman D, Tamassia M, Allphin O, Johnson G. The coding sequence of the bovine ferrochelatase gene. Biochim Biophys Acta. 1995;1231:117-20 pubmed
    ..The bovine code was 86% homologous to the human ferrochelatase code but was altered at a position corresponding to the presumed human initiator codon. ..