Gene Symbol: F2R
Description: coagulation factor II thrombin receptor
Alias: PAR1, proteinase-activated receptor 1, PAR-1, protease-activated receptor 1, thrombin receptor
Species: cow

Top Publications

  1. Suzuki H, Motley E, Eguchi K, Hinoki A, Shirai H, Watts V, et al. Distinct roles of protease-activated receptors in signal transduction regulation of endothelial nitric oxide synthase. Hypertension. 2009;53:182-8 pubmed publisher
    Protease-activated receptors (PARs), such as PAR1 and PAR2, have been implicated in the regulation of endothelial NO production...
  2. Mazor R, Alsaigh T, Shaked H, Altshuler A, Pocock E, Kistler E, et al. Matrix metalloproteinase-1-mediated up-regulation of vascular endothelial growth factor-2 in endothelial cells. J Biol Chem. 2013;288:598-607 pubmed publisher
    ..These results suggest a mechanism by which MMP-1 may prime or sensitize endothelial cell functions. ..