Gene Symbol: EGFR
Description: epidermal growth factor receptor
Alias: epidermal growth factor receptor, epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
Species: cow
Products:     EGFR

Top Publications

  1. Etkovitz N, Tirosh Y, Chazan R, Jaldety Y, Daniel L, Rubinstein S, et al. Bovine sperm acrosome reaction induced by G-protein-coupled receptor agonists is mediated by epidermal growth factor receptor transactivation. Dev Biol. 2009;334:447-57 pubmed publisher
    We have previously demonstrated the presence of active epidermal growth factor receptor (EGFR) and its involvement in sperm capacitation and the acrosome reaction; however, the mechanism of EGFR activation was not clear...
  2. Nelin L, Chicoine L, Reber K, English B, Young T, Liu Y. Cytokine-induced endothelial arginase expression is dependent on epidermal growth factor receptor. Am J Respir Cell Mol Biol. 2005;33:394-401 pubmed
    ..hypothesized that cytokine-induced arginase I and II expression depend on epidermal growth factor (EGF) receptor (EGFR) activity...
  3. Kassab M, Abd Elmaksoud A, Ali M. Localization of the epidermal growth factor (EGF) and epidermal growth factor receptor (EGFR) in the bovine testis. J Mol Histol. 2007;38:207-14 pubmed
    ..In the present investigation we have studied the localization of EGF and EGFR in the adult bovine testis by means of immunohistochemical method...
  4. Langlois S, Nyalendo C, Di Tomasso G, Labrecque L, Roghi C, Murphy G, et al. Membrane-type 1 matrix metalloproteinase stimulates cell migration through epidermal growth factor receptor transactivation. Mol Cancer Res. 2007;5:569-83 pubmed
    ..interaction is permissive to cellular migration through MT1-MMP-dependent transactivation of the epidermal growth factor receptor (EGFR)...
  5. Accornero P, Martignani E, Miretti S, Starvaggi Cucuzza L, Baratta M. Epidermal growth factor and hepatocyte growth factor receptors collaborate to induce multiple biological responses in bovine mammary epithelial cells. J Dairy Sci. 2009;92:3667-75 pubmed publisher
    ..b>Epidermal growth factor receptor and its ligands have also been implicated in the growth and morphogenesis of the mammary epithelium...
  6. Krishnaswamy N, Lacroix Pepin N, Chapdelaine P, Taniguchi H, Kauffenstein G, Chakravarti A, et al. Epidermal growth factor receptor is an obligatory intermediate for oxytocin-induced cyclooxygenase 2 expression and prostaglandin F2 alpha production in bovine endometrial epithelial cells. Endocrinology. 2010;151:1367-74 pubmed publisher
    ..and nonreceptor tyrosine kinases in G protein-coupled receptor signaling, we studied the role of epidermal growth factor receptor (EGFR), c-Src, and phosphoinositide 3-kinase (PI3K) on OT-induced PGF(2 alpha) production in ..
  7. Daniel L, Etkovitz N, Weiss S, Rubinstein S, Ickowicz D, Breitbart H. Regulation of the sperm EGF receptor by ouabain leads to initiation of the acrosome reaction. Dev Biol. 2010;344:650-7 pubmed publisher
    ..This study describes a novel mode of regulation of the sperm epidermal growth factor receptor (EGFR) under physiological conditions and its relevance to the acrosome reaction...
  8. Sagsoz H, Ketani M, Saruhan B. Expression of the erbB/HER receptor family in the bovine uterus during the sexual cycle and the relation of this family to serum sex steroids. Biotech Histochem. 2012;87:105-16 pubmed publisher
    ..05). We demonstrated that the expression of the erbB/HER receptor family varied with different cell types in the bovine uterus during the follicular and luteal phases. ..
  9. Wijayagunawardane M, Hambruch N, Haeger J, Pfarrer C. Effect of epidermal growth factor (EGF) on the phosphorylation of mitogen-activated protein kinase (MAPK) in the bovine oviduct in vitro: Alteration by heat stress. J Reprod Dev. 2015;61:383-9 pubmed publisher
    ..However, these regulatory mechanisms may be compromised in the presence of heat stress (high ambient temperature), leading to low fertility rates and impaired embryo survival. ..