DQB

Summary

Gene Symbol: DQB
Description: MHC class II antigen
Alias: BoLA-DQB, BoLA-DQB1, DQB, DQB1, OLA-DQB, boLa class II histocompatibility antigen, DQB*0101 beta chain, DQB1*1A, MHC class II OLA-DQ-alpha, boLA-DQB, major histocompatibility complex antigen class II, major histocompatibility complex class II
Species: cow
Products:     DQB

Top Publications

  1. Russell G. Sequence duplication at the 3' end of BoLA-DQB genes suggests multiple allelic lineages. Immunogenetics. 2000;52:101-6 pubmed
    Full-length cDNAs encoding the DQB genes expressed by three BoLA class II haplotypes (DH8A, DH15B, and DH24A) were amplified by reverse-transcription polymerase chain reaction, cloned, and sequenced...
  2. Sigurdardottir S, Borsch C, Gustafsson K, Andersson L. Gene duplications and sequence polymorphism of bovine class II DQB genes. Immunogenetics. 1992;35:205-13 pubmed
    ..Four subtypes of bovine DQB genes were found. DQB1 is the major type and was found in almost all haplotypes...
  3. Wang K, Sun D, Xu R, Zhang Y. Identification of 19 new BoLA-DQB alleles. Anim Genet. 2005;36:166-7 pubmed
  4. Norimine J, Brown W. Intrahaplotype and interhaplotype pairing of bovine leukocyte antigen DQA and DQB molecules generate functional DQ molecules important for priming CD4(+) T-lymphocyte responses. Immunogenetics. 2005;57:750-62 pubmed
    Antigen-specific CD4(+) T-lymphocyte responses are restricted by major histocompatibility complex class II molecules, which influence T-cell priming during infection...
  5. Stone R, Muggli Cockett N. Nucleotide sequence of the second exon of a BoLA-DQB gene. Anim Genet. 1992;23:273-4 pubmed
  6. Xu A, Clark T, Teutsch M, Schook L, Lewin H. Sequencing and genetic analysis of a bovine DQB cDNA clone. Anim Genet. 1991;22:381-98 pubmed
    A BoLA-DQB cDNA clone (BoLA-DQ beta-1) was isolated by screening a bovine lymphoblastoid cDNA library with a HLA-DQB genomic clone. The DNA and predicted protein sequences were compared to class II sequences from cattle and other species...
  7. Nilsson P, Marsh S, Joosten I, Nieuwland M, Hensen E, Grosfeld Stulemeyer M, et al. The specificity of anti-HLA class II monoclonal antibodies in cattle. Eur J Immunogenet. 1997;24:211-23 pubmed
    ..Screening of the available bovine DRB3 and DQB exon 2 sequences revealed that some of the key amino acid (AA) motifs of these epitopes were present in cattle as ..

Detail Information

Publications7

  1. Russell G. Sequence duplication at the 3' end of BoLA-DQB genes suggests multiple allelic lineages. Immunogenetics. 2000;52:101-6 pubmed
    Full-length cDNAs encoding the DQB genes expressed by three BoLA class II haplotypes (DH8A, DH15B, and DH24A) were amplified by reverse-transcription polymerase chain reaction, cloned, and sequenced...
  2. Sigurdardottir S, Borsch C, Gustafsson K, Andersson L. Gene duplications and sequence polymorphism of bovine class II DQB genes. Immunogenetics. 1992;35:205-13 pubmed
    ..Four subtypes of bovine DQB genes were found. DQB1 is the major type and was found in almost all haplotypes...
  3. Wang K, Sun D, Xu R, Zhang Y. Identification of 19 new BoLA-DQB alleles. Anim Genet. 2005;36:166-7 pubmed
  4. Norimine J, Brown W. Intrahaplotype and interhaplotype pairing of bovine leukocyte antigen DQA and DQB molecules generate functional DQ molecules important for priming CD4(+) T-lymphocyte responses. Immunogenetics. 2005;57:750-62 pubmed
    Antigen-specific CD4(+) T-lymphocyte responses are restricted by major histocompatibility complex class II molecules, which influence T-cell priming during infection...
  5. Stone R, Muggli Cockett N. Nucleotide sequence of the second exon of a BoLA-DQB gene. Anim Genet. 1992;23:273-4 pubmed
  6. Xu A, Clark T, Teutsch M, Schook L, Lewin H. Sequencing and genetic analysis of a bovine DQB cDNA clone. Anim Genet. 1991;22:381-98 pubmed
    A BoLA-DQB cDNA clone (BoLA-DQ beta-1) was isolated by screening a bovine lymphoblastoid cDNA library with a HLA-DQB genomic clone. The DNA and predicted protein sequences were compared to class II sequences from cattle and other species...
  7. Nilsson P, Marsh S, Joosten I, Nieuwland M, Hensen E, Grosfeld Stulemeyer M, et al. The specificity of anti-HLA class II monoclonal antibodies in cattle. Eur J Immunogenet. 1997;24:211-23 pubmed
    ..Screening of the available bovine DRB3 and DQB exon 2 sequences revealed that some of the key amino acid (AA) motifs of these epitopes were present in cattle as ..