Gene Symbol: COPA
Description: coatomer protein complex subunit alpha
Alias: coatomer subunit alpha, HEP-COP, HEPCOP, alpha-COP, alpha-coat protein
Species: cow
Products:     COPA

Top Publications

  1. Faulstich D, Auerbach S, Orci L, Ravazzola M, Wegchingel S, Lottspeich F, et al. Architecture of coatomer: molecular characterization of delta-COP and protein interactions within the complex. J Cell Biol. 1996;135:53-61 pubmed
    ..We propose that these interactions reflect in vivo associations of those subunits and thus play a functional role in the assembly of coatomer and/or serve to maintain the molecular architecture of the complex. ..
  2. Passreiter M, Anton M, Lay D, Frank R, Harter C, Wieland F, et al. Peroxisome biogenesis: involvement of ARF and coatomer. J Cell Biol. 1998;141:373-83 pubmed
  3. Eugster A, Frigerio G, Dale M, Duden R. COP I domains required for coatomer integrity, and novel interactions with ARF and ARF-GAP. EMBO J. 2000;19:3905-17 pubmed
    ..Glo3p also interacts with intact coatomer in vitro. ..
  4. Pelham H, Rothman J. The debate about transport in the Golgi--two sides of the same coin?. Cell. 2000;102:713-9 pubmed
  5. Lee C, Goldberg J. Structure of coatomer cage proteins and the relationship among COPI, COPII, and clathrin vesicle coats. Cell. 2010;142:123-32 pubmed publisher
  6. Dorshorst B, Henegar C, Liao X, Sällman Almén M, Rubin C, Ito S, et al. Dominant Red Coat Color in Holstein Cattle Is Associated with a Missense Mutation in the Coatomer Protein Complex, Subunit Alpha (COPA) Gene. PLoS ONE. 2015;10:e0128969 pubmed publisher
    ..Here we show that a missense mutation in the coatomer protein complex, subunit alpha (COPA), a gene with previously no known role in pigmentation synthesis, is completely associated with Dominant Red in ..