COL1A1

Summary

Gene Symbol: COL1A1
Description: collagen, type I, alpha 1
Alias: alpha-1 type I collagen, collagen alpha-1(I) chain
Species: cow

Top Publications

  1. ncbi Verification of simple hydration/dehydration methods to characterize multiple water compartments on tendon type 1 collagen
    Ivan L Cameron
    Cellular and Structural Biology Department, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229 3900, USA
    Cell Biol Int 31:531-9. 2007
  2. ncbi Discoidin domain receptor 2 inhibits fibrillogenesis of collagen type 1
    Cosmin Mihai
    Davis Heart and Lung Research Institute, Ohio State University, Columbus, OH 43210, USA
    J Mol Biol 361:864-76. 2006
  3. ncbi The covalent structure of collagen. Amino-acid sequence of peptide 1-CB6-C2
    P P Fietzek
    Eur J Biochem 30:163-8. 1972
  4. doi The aggregation behavior of native collagen in dilute solution studied by intrinsic fluorescence and external probing
    Kun Wu
    National Engineering Laboratory for Clean Technology of Leather Manufacture, Sichuan University, Chengdu 610065, China
    Spectrochim Acta A Mol Biomol Spectrosc 102:186-93. 2013
  5. doi Free axial vibrations at 0 to 200 Hz positively affect extracellular matrix messenger ribonucleic acid expression in bovine nucleus pulposi
    Geoffrey T Desmoulin
    Optima Health Solutions International Corporation KKT International, Vancouver, British Columbia, Canada
    Spine (Phila Pa 1976) 35:1437-44. 2010
  6. doi Delay of cell cycle progression and induction death of cancer cells on type I collagen fibrils [corrected]
    Jun Sasaki
    Nippi Research Institute of Biomatrix, Toride, Ibaraki, Japan
    Connect Tissue Res 52:167-77. 2011
  7. pmc Matrix-specific suppression of integrin activation in shear stress signaling
    A Wayne Orr
    Department of Microbiology, University of Virginia, Charlottesville, VA 22908, USA
    Mol Biol Cell 17:4686-97. 2006
  8. ncbi Advanced granulomatous lesions in Mycobacterium bovis-infected cattle are associated with increased expression of type I procollagen, gammadelta (WC1+) T cells and CD 68+ cells
    A Wangoo
    Department of Pathology, Veterinary Laboratories Agency Weybridge, Addlestone, Surrey, KT15 3NB, UK
    J Comp Pathol 133:223-34. 2005
  9. ncbi Domains and maturation processes that regulate the activity of ADAMTS-2, a metalloproteinase cleaving the aminopropeptide of fibrillar procollagens types I-III and V
    Alain Colige
    Laboratory of Connective Tissues Biology, Center of Biomedical Integrative Genoproteomics, University of Liege, B 4000 SartTilman, Belgium
    J Biol Chem 280:34397-408. 2005
  10. ncbi OIM and related animal models of osteogenesis imperfecta
    J R Shapiro
    Bone Metabolism Research Laboratory, Division of Geriatric Medicine and Gerontology, Johns Hopkins University School of Medicine, Hopkins Bayview Research Campus, Baltimore, Maryland 21224, USA
    Connect Tissue Res 31:265-8. 1995

Scientific Experts

  • Ivan Cameron
  • Kun Wu
  • Jun Sasaki
  • Geoffrey T Desmoulin
  • A Wayne Orr
  • Cosmin Mihai
  • A Wangoo
  • Alain Colige
  • Angeliki Magklara
  • Y Muramatsu
  • Wentao Liu
  • Guoying Li
  • Shunji Hattori
  • Eijiro Adachi
  • Hitomi Fujisaki
  • Shinkichi Irie
  • Christopher J Hunter
  • Carol R Reno
  • Mark H Ginsberg
  • Gunjan Agarwal
  • Martin A Schwartz
  • Hans Deckmyn
  • Sanford J Shattil
  • Terry S Elton
  • Daniel F Iscru
  • Lawrence J Druhan
  • Y Spencer
  • R Ackbar
  • Isabel Vandenberghe
  • D Hicks
  • Betty Nusgens
  • M Vordermeier
  • Charles M Lapiere
  • J Gough
  • Lea Brys
  • L Johnson
  • Alain Beschin
  • S Inglut
  • Florence Ruggiero
  • G Hewinson
  • Jozef Van Beeumen
  • Johanne Dubail
  • Frederic Kesteloot
  • Georgia Sotiropoulou
  • Gregory A Wasney
  • Gerald W Becker
  • Eleftherios P Diamandis
  • Ali A Mellati
  • Sheila P Little
  • B A Konfortov
  • T Yamada
  • H Y Lejukole
  • Y Sasaki
  • Y Taniguchi
  • H Yasue
  • J R Shapiro
  • P P Fietzek
  • G Guerin
  • D J McBride
  • N S Fedarko
  • K Kuhn
  • A Eggen
  • D Bechet
  • P Laurent
  • P Wendt
  • M Ferrara
  • M Nocart
  • D Vaiman
  • J Rauterberg
  • F W Rexrodt
  • R Timpl
  • K von der Mark
  • H Furthmayr
  • F Rexrodt
  • K E Hopper
  • M Stark
  • I Kell

Detail Information

Publications20

  1. ncbi Verification of simple hydration/dehydration methods to characterize multiple water compartments on tendon type 1 collagen
    Ivan L Cameron
    Cellular and Structural Biology Department, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229 3900, USA
    Cell Biol Int 31:531-9. 2007
    ....
  2. ncbi Discoidin domain receptor 2 inhibits fibrillogenesis of collagen type 1
    Cosmin Mihai
    Davis Heart and Lung Research Institute, Ohio State University, Columbus, OH 43210, USA
    J Mol Biol 361:864-76. 2006
    ..Our results demonstrate a novel and important functional role of the DDR2 ECD that may contribute to collagen regulation via modulation of fibrillogenesis...
  3. ncbi The covalent structure of collagen. Amino-acid sequence of peptide 1-CB6-C2
    P P Fietzek
    Eur J Biochem 30:163-8. 1972
  4. doi The aggregation behavior of native collagen in dilute solution studied by intrinsic fluorescence and external probing
    Kun Wu
    National Engineering Laboratory for Clean Technology of Leather Manufacture, Sichuan University, Chengdu 610065, China
    Spectrochim Acta A Mol Biomol Spectrosc 102:186-93. 2013
    ..45, 0.75 and 1.05 mg/mL, the probable characteristic fluorescence peaks for the interactions of proline-aromatic (CH∼π) among the collagen molecules were found at 298 and 316 nm...
  5. doi Free axial vibrations at 0 to 200 Hz positively affect extracellular matrix messenger ribonucleic acid expression in bovine nucleus pulposi
    Geoffrey T Desmoulin
    Optima Health Solutions International Corporation KKT International, Vancouver, British Columbia, Canada
    Spine (Phila Pa 1976) 35:1437-44. 2010
    ..5 g and 0 to 200 Hz. Expression of messenger ribonucleic acid for aggrecan, collagen type I, collagen type II, biglycan, decorin, and versican were assayed, as was apoptosis...
  6. doi Delay of cell cycle progression and induction death of cancer cells on type I collagen fibrils [corrected]
    Jun Sasaki
    Nippi Research Institute of Biomatrix, Toride, Ibaraki, Japan
    Connect Tissue Res 52:167-77. 2011
    ..These results imply that the fibril form of collagen plays a potential role in inhibiting the growth of cancer cells...
  7. pmc Matrix-specific suppression of integrin activation in shear stress signaling
    A Wayne Orr
    Department of Microbiology, University of Virginia, Charlottesville, VA 22908, USA
    Mol Biol Cell 17:4686-97. 2006
    ..Thus, integrins actively cross-inhibit through specific kinase pathways. These mechanisms may determine cellular responses to complex extracellular matrices...
  8. ncbi Advanced granulomatous lesions in Mycobacterium bovis-infected cattle are associated with increased expression of type I procollagen, gammadelta (WC1+) T cells and CD 68+ cells
    A Wangoo
    Department of Pathology, Veterinary Laboratories Agency Weybridge, Addlestone, Surrey, KT15 3NB, UK
    J Comp Pathol 133:223-34. 2005
    ..Such disease correlates may help to inform the development of improved diagnostic methods and support vaccine development programmes...
  9. ncbi Domains and maturation processes that regulate the activity of ADAMTS-2, a metalloproteinase cleaving the aminopropeptide of fibrillar procollagens types I-III and V
    Alain Colige
    Laboratory of Connective Tissues Biology, Center of Biomedical Integrative Genoproteomics, University of Liege, B 4000 SartTilman, Belgium
    J Biol Chem 280:34397-408. 2005
    ..This finding and the existence of multiple processed forms of ADAMTS-2 strongly suggest that ADAMTS-2 may be involved in function(s) other than processing of fibrillar procollagen types I-III...
  10. ncbi OIM and related animal models of osteogenesis imperfecta
    J R Shapiro
    Bone Metabolism Research Laboratory, Division of Geriatric Medicine and Gerontology, Johns Hopkins University School of Medicine, Hopkins Bayview Research Campus, Baltimore, Maryland 21224, USA
    Connect Tissue Res 31:265-8. 1995
    ..This heritable disorder of connective tissue is the result of mutations affecting the COL1A1 and COL1A2 genes of type I collagen...
  11. ncbi Characterization of the enzymatic activity of human kallikrein 6: Autoactivation, substrate specificity, and regulation by inhibitors
    Angeliki Magklara
    Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, 600 University Avenue, Toronto, Ont, Canada M5G 1X5
    Biochem Biophys Res Commun 307:948-55. 2003
    ..Inhibition of hK6 was achieved via binding to different serpins, among which antithrombin III was the most efficient...
  12. ncbi Chromosomal assignments of expressed sequence tags for ACTG1, AHSG, COL1A1, GNAS1, and RPLP1 expressed abundantly in the bovine foetus
    Y Muramatsu
    Department of Food Science, Shizuoka Eiwa College, Ikeda, Shizuoka 422 8005, Japan
    Anim Genet 33:230-1. 2002
  13. ncbi Further characterization of a somatic cell hybrid panel: ten new assignments to the bovine genome
    G Guerin
    Laboratoire de Génétique Biochimique et de Cytogénétique, INRA CRJ, Jouy en Josas, France
    Anim Genet 25:31-5. 1994
    ..This panel was then used to make synteny assignments for 10 additional loci, eight by Southern blotting (COL1A1, COL1A2, FAS, CTSB, CTSL, CHRNG, HEXB and HTR1A) and two by polymerase chain reaction (PCR) amplification (HRH1 ..
  14. ncbi The covalent structure of collagen: amino acid sequence of 1-CB3 from calf skin collagen
    P P Fietzek
    FEBS Lett 26:74-6. 1972
  15. ncbi The covalent structure of collagen. 2. The amino-acid sequence of alpha1-CB7 from calf-skin collagen
    P P Fietzek
    Eur J Biochem 38:396-400. 1973
  16. ncbi The covalent structure of collagen. The amino-acid sequence of the 112-residues. Amino-terminal part of peptide 1-CB6 from calf-skin collagen
    P Wendt
    Eur J Biochem 30:169-83. 1972
  17. ncbi Structural characterization of N-terminal antigenic determinants in calf and human collagen
    J Rauterberg
    Eur J Biochem 27:231-7. 1972
  18. ncbi The covalent structure of collagen: amino-acid sequence of the cyanogen-bromide peptides alpha1-CB2, alpha1-CB4 and alpha1-CB5 from calf-skin collagen
    P P Fietzek
    Eur J Biochem 52:77-82. 1975
    ..Positions 101 and 102 of calf skin collagen are occupied by Asp-Ala, in rat skin collagen by Asn-Thr. The extensive homology in this region is remarkable and is not found in other regions of the alpha1 and alpha2-chain...