Gene Symbol: CASP8
Description: caspase 8
Alias: caspase-8, caspase 8, apoptosis-related cysteine peptidase
Species: cow
Products:     CASP8

Top Publications

  1. Connor E, Cates E, Williams J, Bannerman D. Cloning and radiation hybrid mapping of bovine toll-like receptor-4 (TLR-4) signaling molecules. Vet Immunol Immunopathol. 2006;112:302-8 pubmed
    ..was to clone and sequence the full-length coding regions of bovine genes involved in TLR-4 signaling including CASP8, IRAK1, LY96 (MD-2), TICAM2, TIRAP, TOLLIP and TRAF 6 and to position these genes, as well as MyD88 and TICAM1, on ..
  2. Kuckleburg C, Tiwari R, Czuprynski C. Endothelial cell apoptosis induced by bacteria-activated platelets requires caspase-8 and -9 and generation of reactive oxygen species. Thromb Haemost. 2008;99:363-72 pubmed publisher
    ..These findings suggest that bacterial activation of platelets may contribute to endothelial cell dysfunction observed during sepsis, specifically by inducing endothelial cell apoptosis...
  3. Hu Q, Cui X, Tao L, Xiu L, Wang T, Wang X. Staphylococcus aureus induces apoptosis in primary bovine mammary epithelial cells through Fas-FADD death receptor-linked caspase-8 signaling. DNA Cell Biol. 2014;33:388-97 pubmed publisher
    ..Taken together, our results demonstrated that S. aureus induced apoptosis in pBMECs via the Fas-FADD death receptor and subsequently triggered the caspase-8-dependent signaling. ..