Gene Symbol: mcm10.L
Description: minichromosome maintenance 10 replication initiation factor L homeolog
Alias: mcm10, xmcm10, protein MCM10 homolog, Mcm10p, minichromosome maintenance complex component 10
Species: common platanna

Top Publications

  1. Wawrousek K, Fortini B, Polaczek P, Chen L, Liu Q, Dunphy W, et al. Xenopus DNA2 is a helicase/nuclease that is found in complexes with replication proteins And-1/Ctf4 and Mcm10 and DSB response proteins Nbs1 and ATM. Cell Cycle. 2010;9:1156-66 pubmed
    ..Dna2 co-localizes in foci with RPA and is found in a complex with replication fork components And-1 and Mcm10.  Dna2 interacts with the DSB repair and checkpoint proteins Nbs1 and ATM...
  2. Robertson P, Warren E, Zhang H, Friedman D, Lary J, Cole J, et al. Domain architecture and biochemical characterization of vertebrate Mcm10. J Biol Chem. 2008;283:3338-48 pubmed
    ..and function of vertebrate Mcm10, we have determined the structural architecture of Xenopus laevis Mcm10 (xMcm10) and characterized each domain biochemically...
  3. Robertson P, Chagot B, Chazin W, Eichman B. Solution NMR structure of the C-terminal DNA binding domain of Mcm10 reveals a conserved MCM motif. J Biol Chem. 2010;285:22942-9 pubmed publisher
    ..We have identified the minimal DNA binding region of the XMcm10-CTD and determined its three-dimensional structure by solution NMR...
  4. Chadha G, Gambus A, Gillespie P, Blow J. Xenopus Mcm10 is a CDK-substrate required for replication fork stability. Cell Cycle. 2016;15:2183-2195 pubmed
    ..b>Mcm10 is one of several proteins that have been implicated from work in yeasts to play a role in forming a mature ..
  5. Wohlschlegel J, Dhar S, Prokhorova T, Dutta A, Walter J. Xenopus Mcm10 binds to origins of DNA replication after Mcm2-7 and stimulates origin binding of Cdc45. Mol Cell. 2002;9:233-40 pubmed
    ..Here we report that Xenopus Mcm10 (XMcm10) is not required for origin binding of XMcm2-7...
  6. Warren E, Vaithiyalingam S, Haworth J, Greer B, Bielinsky A, Chazin W, et al. Structural basis for DNA binding by replication initiator Mcm10. Structure. 2008;16:1892-901 pubmed publisher
    b>Mcm10 is an essential eukaryotic DNA replication protein required for assembly and progression of the replication fork...