Gene Symbol: HYD2
Description: iron hydrogenase
Species: Chlamydomonas reinhardtii
Godman J, Molnar A, Baulcombe D, Balk J. RNA silencing of hydrogenase(-like) genes and investigation of their physiological roles in the green alga Chlamydomonas reinhardtii. Biochem J. 2010;431:345-51 pubmed publisher
..Together, our results clearly distinguish the cellular roles of HydA1 and HYD3, and indicate that HYD3, like its yeast and human homologues, has an evolutionary conserved role in the biogenesis or maintenance of cytosolic Fe-S proteins. ..
Meuser J, D Adamo S, Jinkerson R, Mus F, Yang W, Ghirardi M, et al
. Genetic disruption of both Chlamydomonas reinhardtii [FeFe]-hydrogenases: Insight into the role of HYDA2 in H? production. Biochem Biophys Res Commun. 2012;417:704-9 pubmed publisher
..Interestingly, enhanced in vitro and fermentative H(2) production activities were observed in the hydA1-1 hydA2-1 strain complemented with HYDA1, while maximal H(2)-photoproduction rates did not exceed those of wild-type cells...
Liran O, Semyatich R, Milrad Y, Eilenberg H, Weiner I, Yacoby I. Microoxic Niches within the Thylakoid Stroma of Air-Grown Chlamydomonas reinhardtii Protect [FeFe]-Hydrogenase and Support Hydrogen Production under Fully Aerobic Environment. Plant Physiol. 2016;172:264-71 pubmed publisher
..In summary, we show that an anaerobic locality in the chloroplast preserves [FeFe]-hydrogenase activity and supports continuous hydrogen production in air-grown microalgal cells. ..
Long H, Chang C, King P, Ghirardi M, Kim K. Brownian dynamics and molecular dynamics study of the association between hydrogenase and ferredoxin from Chlamydomonas reinhardtii. Biophys J. 2008;95:3753-66 pubmed publisher
..The ferredoxin appeared to form reasonable complexes with the hydrogenase in multiple orientations, some of which were good candidates for inclusion in a transition state ensemble of configurations for electron transfer...
Ghysels B, Godaux D, Matagne R, Cardol P, Franck F. Function of the chloroplast hydrogenase in the microalga Chlamydomonas: the role of hydrogenase and state transitions during photosynthetic activation in anaerobiosis. PLoS ONE. 2013;8:e64161 pubmed publisher
..These two processes are thus important for survival of the cells when they are transiently placed in an anaerobic environment. ..