Gene Symbol: ERVH48-1
Description: endogenous retrovirus group 48 member 1
Alias: suppressyn
Species: chimpanzee

Top Publications

  1. Sugimoto J, Sugimoto M, BERNSTEIN H, Jinno Y, Schust D. A novel human endogenous retroviral protein inhibits cell-cell fusion. Sci Rep. 2013;3:1462 pubmed publisher
    ..Like the syncytins, this protein, called suppressyn, is HERV-derived, placenta-specific and well-conserved over simian evolution...
  2. Malfavon Borja R, Feschotte C. Fighting fire with fire: endogenous retrovirus envelopes as restriction factors. J Virol. 2015;89:4047-50 pubmed publisher
    ..Based on the proposed mode of restriction and the domain architecture of known antiretroviral env, we argue that many more env gene-derived restriction factors await discovery in vertebrate genomes, including the human genome. ..