Gene Symbol: TRIM71
Description: tripartite motif containing 71
Alias: LIN-41, LIN41, E3 ubiquitin-protein ligase TRIM71, RING-type E3 ubiquitin transferase TRIM71, abnormal cell LINeage LIN-41, lin-41 homolog, protein lin-41 homolog, tripartite motif containing 71, E3 ubiquitin protein ligase, tripartite motif-containing 71, tripartite motif-containing protein 71
Species: chicken

Top Publications

  1. Lancman J, Caruccio N, Harfe B, Pasquinelli A, Schageman J, Pertsemlidis A, et al. Analysis of the regulation of lin-41 during chick and mouse limb development. Dev Dyn. 2005;234:948-60 pubmed
    ..elegans let-7 and lin-4. Finally, we show that these miRNAs and others are expressed in the chick limb consistent with the hypothesis that they regulate chicken Lin-41 activity in vivo. ..
  2. Schulman B, Esquela Kerscher A, Slack F. Reciprocal expression of lin-41 and the microRNAs let-7 and mir-125 during mouse embryogenesis. Dev Dyn. 2005;234:1046-54 pubmed
    ..Our results suggest that mammalian lin-41 is temporally regulated by miRNAs in order to direct key developmental events such as limb formation. ..
  3. Kanamoto T, Terada K, Yoshikawa H, Furukawa T. Cloning and regulation of the vertebrate homologue of lin-41 that functions as a heterochronic gene in Caenorhabditis elegans. Dev Dyn. 2006;235:1142-9 pubmed
    ..The 3'UTRs of the mouse and chick lin-41 genes contain multiple let-7 complementary sites. Using luciferase assay, we showed that lin-41 expression can be regulated through let-7 complementary sites. ..