TFAP2A

Summary

Gene Symbol: TFAP2A
Description: transcription factor AP-2 alpha
Alias: TFAP2, transcription factor AP-2-alpha, AP-2 transcription factor, transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha), transcription factor AP2
Species: chicken
Products:     TFAP2A

Top Publications

  1. Shen H, Wilke T, Ashique A, Narvey M, Zerucha T, Savino E, et al. Chicken transcription factor AP-2: cloning, expression and its role in outgrowth of facial prominences and limb buds. Dev Biol. 1997;188:248-66 pubmed
    ..Application of an FGF-4 soaked bead to the apex of the limb bud maintained AP-2 expression. Thus AP-2 is involved in outgrowth and could be regulated by factors such as FGFs that are present in the ectoderm of both the face and limb. ..
  2. Mitchell D, DiMario J. AP-2 alpha suppresses skeletal myoblast proliferation and represses fibroblast growth factor receptor 1 promoter activity. Exp Cell Res. 2010;316:194-202 pubmed publisher
    ..In total, these results indicate that AP-2 alpha is a transcriptional repressor of FGFR1 gene expression during skeletal myogenesis. ..
  3. Xu X, Liu Z, Huang H, Zheng K, Hu X, Zhang Z, et al. AP-2? and AP-2? regulate dorsal interneuron specification in the spinal cord. Neuroscience. 2017;340:232-242 pubmed publisher
    ..Together, our studies indicated that AP-2 family members, AP-2? and AP-2?, have distinct functions in the regulation of dorsal interneuron development. ..