steroidogenic factor 1


Gene Symbol: steroidogenic factor 1
Description: nuclear receptor subfamily 5 group A member 1
Alias: Ad4BP, SF-1, steroidogenic factor 1, adrenal 4 binding protein
Species: chicken
Products:     steroidogenic factor 1

Top Publications

  1. Wang J, Gong Y. Transcription of CYP19A1 is directly regulated by SF-1 in the theca cells of ovary follicles in chicken. Gen Comp Endocrinol. 2017;247:1-7 pubmed publisher
    ..Here, we found that CYP19A1 was only expressed in the theca cell layers of chicken ovary follicles. Steroidogenic factor 1 (SF-1, also named as nuclear receptor subfamily 5 group A member 1, NR5A1), a potential regulators, was ..
  2. Kudo T, Sutou S. Molecular cloning of chicken FTZ-F1-related orphan receptors. Gene. 1997;197:261-8 pubmed
    ..Moreover, SF-1/Ad4BP plays a critical role in the sexual differentiation of gonads in mammals...
  3. Miao N, Wang X, Hou Y, Feng Y, Gong Y. Identification of male-biased microRNA-107 as a direct regulator for nuclear receptor subfamily 5 group A member 1 based on sexually dimorphic microRNA expression profiling from chicken embryonic gonads. Mol Cell Endocrinol. 2016;429:29-40 pubmed publisher
    ..Overall results indicate that miR-107 may specifically mediate avian ovary-development by post-transcriptional regulation of NR5a1 and CYP19A1 in estrogen signaling pathways...
  4. Takada S, Wada T, Kaneda R, Choi Y, Yamashita Y, Mano H. Evidence for activation of Amh gene expression by steroidogenic factor 1. Mech Dev. 2006;123:472-80 pubmed publisher
    ..The sequence of the proximal promoter of Amh contains a putative binding site for steroidogenic factor 1 (SF1), the protein product of which can up-regulate Amh in mammals...
  5. Endo D, Murakami S, Akazome Y, Park M. Sex difference in Ad4BP/SF-1 mRNA expression in the chick-embryo brain before gonadal sexual differentiation. Zoolog Sci. 2007;24:877-82 pubmed
    ..5 of incubation and in all brain samples after day 6 of incubation. The mRNA of Ad4BP/SF-1, a transcription factor that regulates steroidogenic enzymes, showed higher expression levels in the male ..