Gene Symbol: SREBF1
Description: sterol regulatory element binding transcription factor 1
Alias: SREBP-1, SREBP1, sterol regulatory element-binding protein 1, sterol regulatory element binding protein 1
Yin L, Zhang Y, Hillgartner F. Sterol regulatory element-binding protein-1 interacts with the nuclear thyroid hormone receptor to enhance acetyl-CoA carboxylase-alpha transcription in hepatocytes. J Biol Chem. 2002;277:19554-65 pubmed
..Here, we also show that alterations in SREBP expression play a role in mediating cell type-dependent differences in T3 regulation of ACCalpha transcription. ..
Assaf S, Lagarrigue S, Daval S, Sansom M, Leclercq B, Michel J, et al
. Genetic linkage and expression analysis of SREBP and lipogenic genes in fat and lean chicken. Comp Biochem Physiol B Biochem Mol Biol. 2004;137:433-41 pubmed
..These results emphasised the interest to perform expression and genetic linkage studies jointly, to progress in identifying the genetic origin of variability of a quantitative trait. ..
Seol H, Sato K, Matsubara Y, Schneider W, Akiba Y. Modulation of sterol regulatory element binding protein-2 in response to rapid follicle development in chickens. Comp Biochem Physiol B Biochem Mol Biol. 2007;147:698-703 pubmed
..These results suggest that SREBP-2, which might be regulated by LXRalpha, is involved in the rapid growth stages of follicle development in avian species. ..
Park H, Zhang Y, DU C, Welzig C, Madias C, Aronovitz M, et al
. Role of SREBP-1 in the development of parasympathetic dysfunction in the hearts of type 1 diabetic Akita mice. Circ Res. 2009;105:287-94 pubmed publisher
Wang L, Na W, Wang Y, Wang Y, Wang N, Li Y, et al
. [Chicken SREBP1 gene antiserums preparation and its tissue expression characterization]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2010;26:1241-5 pubmed
The aim of this study was to prepare the antiserums against chicken sterol regulatory element binding protein1 (SREBP1), and to analyze the expression of SREBP1 in chicken tissues...
Fu R, Liu R, Zhao G, Zheng M, Chen J, Wen J. Expression profiles of key transcription factors involved in lipid metabolism in Beijing-You chickens. Gene. 2014;537:120-5 pubmed publisher
..Taken together, all five transcription factors studied play roles in lipid metabolism in chickens with C/EBP? and PPAR? being important effectors. ..
Li Q, Zhao X, Gilbert E, Liu Y, Wang Y, Qiu M, et al
. Confined housing system increased abdominal and subcutaneous fat deposition and gene expressions of carbohydrate response element-binding protein and sterol regulatory element-binding protein 1 in chicken. Genet Mol Res. 2015;14:1220-8 pubmed publisher
..carbohydrate response element-binding protein (ChREBP), sterol regulatory element-binding protein-1 (SREBP1), and fatty acid synthase were detected...
Gondret F, Ferr P, Dugail I. ADD-1/SREBP-1 is a major determinant of tissue differential lipogenic capacity in mammalian and avian species. J Lipid Res. 2001;42:106-13 pubmed
..Gondret, F., P. Ferré, and I. Dugail. ADD-1/SREBP-1 is a major determinant of tissue differential lipogenic capacity in mammalian and avian species. J. Lipid Res. 2001. 42: 106;-113...
Talukdar S, Hillgartner F. The mechanism mediating the activation of acetyl-coenzyme A carboxylase-alpha gene transcription by the liver X receptor agonist T0-901317. J Lipid Res. 2006;47:2451-61 pubmed