Gene Symbol: SP3
Description: Sp3 transcription factor
Alias: transcription factor Sp3
Moreno González G, López Colomé A, Rodriguez G, Zarain Herzberg A. Transcription of the chicken Grin1 gene is regulated by the activity of SP3 and NRSF in undifferentiated cells and neurons. Biosci Rep. 2008;28:177-88 pubmed publisher
..neuron-restrictive silencing factor), and one SP (stimulating protein transcription factor) element that binds SP3, both repressing Grin1 gene transcription in undifferentiated P19 cells (embryonic terato-carcinoma cells) and PC12 ..
Hübner K, Phi van L. Sp1 and Sp3 regulate transcription of the chicken GAS41 gene. Biochim Biophys Acta. 2010;1799:442-7 pubmed publisher
..Electrophoretic mobility shift assays and chromatin immunoprecipitation analyses revealed that Sp1 and Sp3 bind to this promoter...
Chamboredon S, Briggs J, Vial E, Hurault J, Galvagni F, Oliviero S, et al
. v-Jun downregulates the SPARC target gene by binding to the proximal promoter indirectly through Sp1/3. Oncogene. 2003;22:4047-61 pubmed
..assays in Sp1/3-deficient Drosophila SL2 cells and in chick embryo fibroblasts, we show that (i) Sp1 and/or Sp3 is required for constitutive activation of SPARC transcription, by binding directly to the GGA-rich -92/-57 ..
Chamboredon S, Castellazzi M. v-Jun downregulates the alpha 2 (I) collagen target gene indirectly through Sp1/3. Oncogene. 2005;24:2547-57 pubmed
..showed that (i) high constitutive activity of -433/+11 requires a direct binding of the ubiquitous Sp1 and/or Sp3 transcription factors acting on two distinct motifs, that is, a proximal TCC-rich region and an upstream GC box, ..
Magee C, Nurminskaya M, Faverman L, Galera P, Linsenmayer T. SP3/SP1 transcription activity regulates specific expression of collagen type X in hypertrophic chondrocytes. J Biol Chem. 2005;280:25331-8 pubmed
..In the present study, we examined the role of SP3/SP1 transcription factors in the regulation of the Col10a1 promoter...