SKI

Summary

Gene Symbol: SKI
Description: SKI proto-oncogene
Alias: C-SKI, v-ski, ski oncogene, proto-oncogene c-Ski, v-ski avian sarcoma viral oncogene homolog, v-ski sarcoma viral oncogene homolog
Species: chicken
Products:     SKI

Top Publications

  1. Dahl R, Wani B, Hayman M. The Ski oncoprotein interacts with Skip, the human homolog of Drosophila Bx42. Oncogene. 1998;16:1579-86 pubmed
    The v-Ski avian retroviral oncogene is postulated to act as a transcription factor...
  2. Cohen S, Zheng G, Heyman H, Stavnezer E. Heterodimers of the SnoN and Ski oncoproteins form preferentially over homodimers and are more potent transforming agents. Nucleic Acids Res. 1999;27:1006-14 pubmed
    sno is a member of the ski oncogene family and shares ski 's ability to transform avian fibroblasts and induce muscle differentiation. Ski and SnoN are transcription factors that form both homodimers and heterodimers...
  3. Ye F, Lemieux H, Hoppel C, Hanson R, Hakimi P, Croniger C, et al. Peroxisome proliferator-activated receptor ? (PPAR?) mediates a Ski oncogene-induced shift from glycolysis to oxidative energy metabolism. J Biol Chem. 2011;286:40013-24 pubmed publisher
    Overexpression of the Ski oncogene induces oncogenic transformation of chicken embryo fibroblasts (CEFs). However, unlike most other oncogene-transformed cells, Ski-transformed CEFs (Ski-CEFs) do not display the classical Warburg effect...
  4. Sutrave P, Hughes S. Isolation and characterization of three distinct cDNAs for the chicken c-ski gene. Mol Cell Biol. 1989;9:4046-51 pubmed
    Three types of c-ski cDNAs have been isolated from two different chicken cDNA libraries. Sequence comparisons suggest that the cDNAs derive from alternatively spliced mRNAs...
  5. Kim K, Sampson E, Maynard R, O Keefe R, Chen D, Drissi H, et al. Ski inhibits TGF-?/phospho-Smad3 signaling and accelerates hypertrophic differentiation in chondrocytes. J Cell Biochem. 2012;113:2156-66 pubmed publisher
    ..One such negative regulator, Ski, is an oncoprotein that is known to inhibit TGF-?/Smad3 signaling via its interaction with phospho-Smad3 and ..